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Fig. 4 | BMC Molecular and Cell Biology

Fig. 4

From: An Endostatin-lentivirus (ES-LV)-EPC gene therapy agent for suppression of neovascularization in oxygen-induced retinopathy rat model

Fig. 4

Neovascularization leakage areas analysis (IOD/Area, comparison in 5 groups). a Neovascularization leakage areas analysis at 1 h. b Neovascularization leakage areas analysis at 1d. c Neovascularization leakage areas analysis at 3d. d Neovascularization leakage areas analysis at 5d. *P < 0.05, **P < 0.01 as compared with Blank; ##P < 0.01, ###P < 0.001 as compared with OIR + NC. IOD: integral optical density. Blank: blank control group (age-matched rats kept in constant normoxia with non-intravitreal injection); OIR + NC (negative control group): oxygen-induced retinopathy (OIR) rats with empty-lentivirus intravitreal injection; OIR + ES-LV: OIR rats with endostatin-lentivirus intravitreal injection; OIR + EPCs: OIR rats with EPCs intravitreal injection; OIR + ES-LV-EPCs: OIR rats with endostatin-lentivirus-EPCs intravitreal injection

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