Fig. 8
From: Role of tumor cell senescence in non-professional phagocytosis and cell-in-cell structure formation
Kaplan Meier plots for overall survival of intraepithelial senescent cell density/mm2 and cell-in-cell phenomena density/mm2. The cut-off values were determined by the ROC curve analysis. This resulted in specific cut off values for each individual analysis. The five-year survival rate is given in brackets after the designation of the corresponding cut-off values. All graphs in the left column show high and/or low rates of senescent cells combined with high and/or low cell-in-cell events. a biopsies. b central tumor, c invasive tumor front and d normal tissue from the tumor resection. The graphs in the right column compare high senescence and high cell-in-cell rates to all other combinations. e biopsies. f central tumor, g invasive front and h the normal tissue from the tumor resection. Five-year survival rate is shown in brackets (f) and (h). Statistical significance was checked by the log-rank test