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Fig. 2 | BMC Molecular and Cell Biology

Fig. 2

From: circRNA_0005529 facilitates growth and metastasis of gastric cancer via regulating miR-527/Sp1 axis

Fig. 2

circ_0005529 could promote the proliferation of GC cells. a Relative circ_0005529 expression levels in Lv-NC or Lv-circ_0005529 HGC-27 cells and sh-NC or sh-circ_0005529 (sh-#1circ_0005529, sh-#2circ_0005529) MKN-45 cells. b Growth curves of HGC-27 cells (Lv-NC or Lv-circ_0005529) and MKN-45 cells (sh-NC or sh-circ_0005529) at 0 h, 24 h, 48 h, 72 h and 96 h. Measurements of the cell growth rate were obtained using a MTT cell proliferation assay kit. c Representative profiles of EDU cell growth in HGC-27 cells (Lv-NC or Lv-circ_0005529) and MKN-45 cells (sh-NC or sh-circ_0005529). EDU incorporation rate were quantified. d Colony formation analysis of HGC-27 cells (Lv-NC or Lv-circ_0005529) and MKN-45 cells (sh-NC or sh-circ_0005529). Percentage of colony area were quantified. (Mean ± SEM, * p < 0.05, ** p < 0.01)

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