Fig. 3
From: High D-glucose levels induce ACE2 expression via GLUT1 in human airway epithelial cell line Calu-3
Inhibition of Glucose transporter (GLUT) gene in Calu-3 cells. The effects of GLUT1 inhibitor (BAY-876) on ACE2 expression were analyzed by real-time PCR (a) and western blotting (b, c) after 72 h of treatment. Data are presented as mean ± SD (n = 4). Symbol (*) indicates statistical differences (p < 0.05). d GLUT-1 mRNA was suppressed after GLUT-1 siRNA treatment for 24 h. e SiRNA-mediated knockdown of GLUT1 suppressed ACE2 mRNA in Calu-3 cells. Data are presented as mean ± SD (n = 3). Symbol (*) indicates statistical differences (p < 0.05)