Fig. 3
From: CARD9 contributes to ovarian cancer cell proliferation, cycle arrest, and cisplatin sensitivity
Effects of CARD9 on cycle arrest and cisplatin sensitivity. A Cell cycle distribution was assessed by flow cytometry. B The levels of cycle-related proteins in cells were detected by immunoblotting. C CARD9 levels in SKOV3/DDP and SKOV3 cell lines were determined using RT-qPCR and (D) immunoblotting. E The effect of different concentrations of DDP on the viability of SKOV3 and SKOV3/DDP cell lines was determined using the CCK8 assay. F, G The level of apoptosis was assessed by TUNEL staining and (H) immunoblotting. *P < 0.05, ***P < 0.001 vs. sh-NC or SKOV3; ###P < 0.001 vs. SKOV3/DDP + sh-NC