Fig. 2

Hyperoxia-exposure upregulated Dvl-1 protein expression and activated Wnt/β-catenin signaling pathway in newborn rat lung. A Expression of β-catenin, Dvl-1, CTNNBL1 and cyclin D1 proteins levels by western blot 1: normoxia exposure on 3rd day, 2: hyperoxia exposure on 3rd day, 3: normoxia exposure on 7th day, 4: hyperoxia exposure on 7th day, 5: normoxia exposure on 14th day, 6: hyperoxia exposure on 14th day. B Normalized against GAPDH. C Expression of β-catenin, Dvl-1, CTNNBL1 and cyclin D1 mRNA levels by real-time PCR and normalized against Gapdh, *p < 0. 05, **p < 0. 01 was considered statistically significant