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Fig. 2 | BMC Molecular and Cell Biology

Fig. 2

From: Prioritization of Trypanosoma brucei editosome protein interactions interfaces at residue resolution through proteome-scale network analysis

Fig. 2

The modeled structures of central RESC PPIs from the editosome of T. brucei: (a) RESC2-RESC1 PPI, solid black arrows show the beta-barrels of each protein, and the dotted squares show the beta-hairpins; (b) RESC12A-RESC13 PPI; (c) RESC6-RESC 10 PPI. The upper figure for each PPI is the space filling mode of the PPI structure in which the dotted arrows pinpoint core holes potentially needed for RNA binding. Blue lines are the interactions between interface residues of the two interactors (PAE max 5Å, distance max 5Å). Top 3 hotspots of each PPI are labeled and are shown in red with the sidechains visible

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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