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Figure 7 | BMC Cell Biology

Figure 7

From: Human adipose tissue-derived multilineage progenitor cells exposed to oxidative stress induce neurite outgrowth in PC12 cells through p38 MAPK signaling

Figure 7

Model of this study. A schematic illustration of the results of this study is shown. Oxidative stress by BSO treatment in hADMPCs results in p38 MAPK activation, which then leads to BMP2 and FGF2 expression and secretion. The secreted factors then bind to the receptors on PC12 cells, facilitating neural differentiation in these cells.

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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