Martin P: Wound healing--aiming for perfect skin regeneration. Science. 1997, 276 (5309): 75-81. 10.1126/science.276.5309.75.
Article
CAS
PubMed
Google Scholar
Tumbar T, Guasch G, Greco V, Blanpain C, Lowry WE, Rendl M, Fuchs E: Defining the epithelial stem cell niche in skin. Science. 2004, 303 (5656): 359-363. 10.1126/science.1092436.
Article
PubMed Central
CAS
PubMed
Google Scholar
Blanpain C, Lowry WE, Geoghegan A, Polak L, Fuchs E: Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell. 2004, 118 (5): 635-648. 10.1016/j.cell.2004.08.012.
Article
CAS
PubMed
Google Scholar
Zuk PA, Zhu M, Ashjian P, De Ugarte DA, Huang JI, Mizuno H, Alfonso ZC, Fraser JK, Benhaim P, Hedrick MH: Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell. 2002, 13 (12): 4279-4295. 10.1091/mbc.E02-02-0105.
Article
PubMed Central
CAS
PubMed
Google Scholar
Fathke C, Wilson L, Hutter J, Kapoor V, Smith A, Hocking A, Isik F: Contribution of bone marrow-derived cells to skin: collagen deposition and wound repair. Stem Cells. 2004, 22 (5): 812-822. 10.1634/stemcells.22-5-812.
Article
PubMed Central
PubMed
Google Scholar
Veeman MT, Axelrod JD, Moon RT: A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling. Dev Cell. 2003, 5 (3): 367-377. 10.1016/S1534-5807(03)00266-1.
Article
CAS
PubMed
Google Scholar
Reya T, Clevers H: Wnt signalling in stem cells and cancer. Nature. 2005, 434 (7035): 843-850. 10.1038/nature03319.
Article
CAS
PubMed
Google Scholar
Gat U, DasGupta R, Degenstein L, Fuchs E: De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin. Cell. 1998, 95 (5): 605-614. 10.1016/S0092-8674(00)81631-1.
Article
CAS
PubMed
Google Scholar
Huelsken J, Vogel R, Brinkmann V, Erdmann B, Birchmeier C, Birchmeier W: Requirement for beta-catenin in anterior-posterior axis formation in mice. J Cell Biol. 2000, 148 (3): 567-578. 10.1083/jcb.148.3.567.
Article
PubMed Central
CAS
PubMed
Google Scholar
Reddy S, Andl T, Bagasra A, Lu MM, Epstein DJ, Morrisey EE, Millar SE: Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis. Mech Dev. 2001, 107 (1-2): 69-82. 10.1016/S0925-4773(01)00452-X.
Article
CAS
PubMed
Google Scholar
Saitoh A, Hansen LA, Vogel JC, Udey MC: Characterization of Wnt gene expression in murine skin: possible involvement of epidermis-derived Wnt-4 in cutaneous epithelial- mesenchymal interactions. Exp Cell Res. 1998, 243 (1): 150-160. 10.1006/excr.1998.4152.
Article
CAS
PubMed
Google Scholar
DasGupta R, Fuchs E: Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation. Development. 1999, 126 (20): 4557-4568.
CAS
PubMed
Google Scholar
Maretto S, Cordenonsi M, Dupont S, Braghetta P, Broccoli V, Hassan AB, Volpin D, Bressan GM, Piccolo S: Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors. Proc Natl Acad Sci U S A. 2003, 100 (6): 3299-3304. 10.1073/pnas.0434590100.
Article
PubMed Central
CAS
PubMed
Google Scholar
Klein PS, Melton DA: A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci U S A. 1996, 93 (16): 8455-8459. 10.1073/pnas.93.16.8455.
Article
PubMed Central
CAS
PubMed
Google Scholar
Wilson L, Fathke C, Isik F: Tissue dispersion and flow cytometry for the cellular analysis of wound healing. Biotechniques. 2002, 32 (3): 548-551.
CAS
PubMed
Google Scholar
He X, Saint-Jeannet JP, Wang Y, Nathans J, Dawid I, Varmus H: A member of the Frizzled protein family mediating axis induction by Wnt- 5A. Science. 1997, 275 (5306): 1652-1654. 10.1126/science.275.5306.1652.
Article
CAS
PubMed
Google Scholar
Wagers AJ, Weissman IL: Plasticity of adult stem cells. Cell. 2004, 116 (5): 639-648. 10.1016/S0092-8674(04)00208-9.
Article
CAS
PubMed
Google Scholar
Korbling M, Estrov Z: Adult stem cells for tissue repair - a new therapeutic concept?. N Engl J Med. 2003, 349 (6): 570-582. 10.1056/NEJMra022361.
Article
PubMed
Google Scholar
Alonso L, Fuchs E: Stem cells in the skin: waste not, Wnt not. Genes Dev. 2003, 17 (10): 1189-1200. 10.1101/gad.1086903.
Article
CAS
PubMed
Google Scholar
Jiang Y, Jahagirdar BN, Reinhardt RL, Schwartz RE, Keene CD, Ortiz-Gonzalez XR, Reyes M, Lenvik T, Lund T, Blackstad M, Du J, Aldrich S, Lisberg A, Low WC, Largaespada DA, Verfaillie CM: Pluripotency of mesenchymal stem cells derived from adult marrow. Nature. 2002, 418 (6893): 41-49. 10.1038/nature00870.
Article
CAS
PubMed
Google Scholar
Toma JG, Akhavan M, Fernandes KJ, Barnabe-Heider F, Sadikot A, Kaplan DR, Miller FD: Isolation of multipotent adult stem cells from the dermis of mammalian skin. Nat Cell Biol. 2001, 3 (9): 778-784. 10.1038/ncb0901-778.
Article
CAS
PubMed
Google Scholar
Watt FM, Hogan BL: Out of Eden: stem cells and their niches. Science. 2000, 287 (5457): 1427-1430. 10.1126/science.287.5457.1427.
Article
CAS
PubMed
Google Scholar
Gage FH: Mammalian neural stem cells. Science. 2000, 287 (5457): 1433-1438. 10.1126/science.287.5457.1433.
Article
CAS
PubMed
Google Scholar
Martin P, D'Souza D, Martin J, Grose R, Cooper L, Maki R, McKercher SR: Wound healing in the PU.1 null mouse--tissue repair is not dependent on inflammatory cells. Curr Biol. 2003, 13 (13): 1122-1128. 10.1016/S0960-9822(03)00396-8.
Article
CAS
PubMed
Google Scholar
St-Jacques B, Dassule HR, Karavanova I, Botchkarev VA, Li J, Danielian PS, McMahon JA, Lewis PM, Paus R, McMahon AP: Sonic hedgehog signaling is essential for hair development. Curr Biol. 1998, 8 (19): 1058-1068. 10.1016/S0960-9822(98)70443-9.
Article
CAS
PubMed
Google Scholar
Mill P, Mo R, Fu H, Grachtchouk M, Kim PC, Dlugosz AA, Hui CC: Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development. Genes Dev. 2003, 17 (2): 282-294. 10.1101/gad.1038103.
Article
PubMed Central
CAS
PubMed
Google Scholar
Waikel RL, Kawachi Y, Waikel PA, Wang XJ, Roop DR: Deregulated expression of c-Myc depletes epidermal stem cells. Nat Genet. 2001, 28 (2): 165-168. 10.1038/88889.
Article
CAS
PubMed
Google Scholar
Honeycutt KA, Roop DR: c-Myc and epidermal stem cell fate determination. J Dermatol. 2004, 31 (5): 368-375.
Article
CAS
PubMed
Google Scholar
Niemann C, Owens DM, Hulsken J, Birchmeier W, Watt FM: Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours. Development. 2002, 129 (1): 95-109.
CAS
PubMed
Google Scholar
Lo Celso C, Prowse DM, Watt FM: Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours. Development. 2004, 131 (8): 1787-1799. 10.1242/dev.01052.
Article
CAS
PubMed
Google Scholar
Weeraratna AT, Jiang Y, Hostetter G, Rosenblatt K, Duray P, Bittner M, Trent JM: Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma. Cancer Cell. 2002, 1 (3): 279-288. 10.1016/S1535-6108(02)00045-4.
Article
CAS
PubMed
Google Scholar
Tsou R, Fathke C, Wilson L, Wallace K, Gibran N, Isik F: Retroviral delivery of dominant-negative vascular endothelial growth factor receptor type 2 to murine wounds inhibits wound angiogenesis. Wound Repair Regen. 2002, 10 (4): 222-229. 10.1046/j.1524-475X.2002.10405.x.
Article
PubMed
Google Scholar
Gibran NS, Tamura R, Tsou R, Isik FF: Human dermal microvascular endothelial cells produce nerve growth factor: implications for wound repair. Shock. 2003, 19 (2): 127-130. 10.1097/00024382-200302000-00007.
Article
CAS
PubMed
Google Scholar
Grignani F, Kinsella T, Mencarelli A, Valtieri M, Riganelli D, Lanfrancone L, Peschle C, Nolan GP, Pelicci PG: High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein. Cancer Res. 1998, 58 (1): 14-19.
CAS
PubMed
Google Scholar
Nolan G: . 2005, [http://www.stanford.edu/group/nolan/]