Figure 7
From: Cheiradone: a vascular endothelial cell growth factor receptor antagonist
Investigation of the cytotoxic effect of cheiradone on BAEC and HDMEC viability. The cytotoxic effect of cheiradone was determined using (A) MTT assay and (B) Active-caspase-3 apoptosis assay. Cells were incubated with cheiradone and staurosporine (1.4 μM) for 24 h. Values significantly different from the control (DMSO) are shown by *. Immunofluorescence photomicrographs for HMDEC were taken as described above and show. (C) control, DMSO (D s taurosporine, the arrow indicates a positively stained apoptotic cell and (E) cheiradone.