Folkman J: Angiogenesis: an organizing principle for drug discovery?. Nat Rev Drug Discov. 2007, 6: 273-86. 10.1038/nrd2115.
Article
CAS
PubMed
Google Scholar
Hillen F, Griffioen AW: Tumour vascularization: sprouting angiogenesis and beyond. Cancer Metastasis Rev. 2007 Aug 24,
Shima DT, Adamis AP, Ferrara N, Yeo KT, Yeo TK, Allende R, Folkman J, D'Amore PA: Hypoxic induction of endothelial cell growth factors in retinal cells: identification and characterization of vascular endothelial growth factor (VEGF) as the mitogen. Mol Med. 1995, 1: 182-193.
PubMed Central
CAS
PubMed
Google Scholar
Li Z, Shimada Y, Uchida S, Maeda M, Kawabe A, Mori A, Itami A, Kano M, Watanabe G, Imamura M: TGF-alpha as well as VEGF, PD-ECGF and bFGF contribute to angiogenesis of esophageal squamous cell carcinoma. Int J Oncol. 2000, 17: 453-460.
CAS
PubMed
Google Scholar
Milkiewicz M, Ispanovic E, Doyle JL, Haas TL: Regulators of angiogenesis and strategies for their therapeutic manipulation. Int J Biochem Cell iol. 2006, 38: 333-357. 10.1016/j.biocel.2005.10.006.
Article
CAS
Google Scholar
Morisada T, Kubota Y, Urano T, Suda T, Oike Y: Angiopoietins and angiopoietin-like proteins in angiogenesis. Endothelium. 2006, 13: 71-79. 10.1080/10623320600697989.
Article
CAS
PubMed
Google Scholar
Ferrara N, Gerber HP, LeCouter J: The biology of VEGF and its receptors. Nat Med. 2003, 9: 669-676. 10.1038/nm0603-669.
Article
CAS
PubMed
Google Scholar
Takahashi H, Shibuya M: The vascular endothelial growth factor VEGF/VEGF receptor system and its role under physiological and pathological conditions. Clin Sci (Lond). 2005, 109: 227-241.
Article
CAS
Google Scholar
McNamara DA, Harmey J, Wang JH, Kay E, Walsh TN, Bouchier-Hayes DJ: Tamoxifen inhibits endothelial cell proliferation and attenuates VEGF-mediated angiogenesis and migration in vivo. Eur J Surg Oncol. 2001, 27: 714-718. 10.1053/ejso.2001.1177.
Article
CAS
PubMed
Google Scholar
Parenti A, Bellik L, Brogelli L, Filippi S, Ledda F: Endogenous VEGF-A is responsible for mitogenic effects of MCP-1 on vascular smooth muscle cells. Am J Physiol Heart Circ Physiol. 2004, 286: H1978-1984. 10.1152/ajpheart.00414.2003.
Article
CAS
PubMed
Google Scholar
Liang D, Chang JR, Chin AJ, Smith A, Kelly C, Weinberg ES, Ge R: The role of vascular endothelial growth factor (VEGF) in vasculogenesis, angiogenesis and hematopoiesis in zebrafish development. Mech Dev. 2001, 108: 29-43. 10.1016/S0925-4773(01)00468-3.
Article
CAS
PubMed
Google Scholar
Nagy JA, Dvorak AM, Dvorak HF: EGF-A(164/165) and PlGF: roles in angiogenesis and arteriogenesis. Trends Cardiovasc Med. 2003, HKJ: 169-175. 10.1016/S1050-1738(03)00056-2.
Article
Google Scholar
Conejo-Garcia JR, Benencia F, Courreges MC, Kang E, Mohamed-Hadley A, Buckanovich RJ, Holtz DO, Jenkins A, Na H, Zhang L, Wagner DS, Katsaros D, Caroll R, Coukos G: Tumor-infiltrating dendritic cell precursors recruited by a beta-defensin contribute to vasculogenesis under the influence of VEGF-A. Nat Med. 2004, 10: 950-958. 10.1038/nm1097.
Article
CAS
PubMed
Google Scholar
Hoeben A, Landuyt B, Highley MS, Wildiers H, Van Oosterom AT, De Bruijn EA: Vascular endothelial growth factor and angiogenesis. Pharmacol Rev. 2004, 56: 549-580. 10.1124/pr.56.4.3.
Article
CAS
PubMed
Google Scholar
Eming SA, Krieg T: Molecular mechanisms of VEGF-A action during tissue repair. J Investig Dermatol Symp Proc. 2006, 11: 79-86. 10.1038/sj.jidsymp.5650016.
Article
CAS
PubMed
Google Scholar
Shibuya M: Vascular endothelial growth factor receptor-1 (VEGFR-1/Flt-1): a dual regulator for angiogenesis. Angiogenesis. 2006, 9: 225-230. 10.1007/s10456-006-9055-8.
Article
CAS
PubMed
Google Scholar
Zilberberg L, Shinkaruk S, Lequin O, Rousseau B, Hagedorn M, Costa F, Caronzolo D, Balke M, Canron X, Convert O, Lain G, Gionnet K, Goncalves M, Bayle M, Bello L, Chassaing G, Deleris G, Bikfalvi A: Structure and inhibitory effects on angiogenesis and tumor development of a new vascular endothelial growth factor inhibitor. J Biol Chem. 2003, 12;278: 35564-35573. 10.1074/jbc.M304435200.
Article
Google Scholar
Byrne AM, Bouchier-Hayes DJ, Harmey JH: Angiogenic and cell survival functions of vascular endothelial growth factor (VEGF). J Cell Mol Med. 2005, 9: 777-794. 10.1111/j.1582-4934.2005.tb00379.x.
Article
CAS
PubMed
Google Scholar
Kramer I, Lipp HP: Bevacizumab, a humanized anti-angiogenic monoclonal antibody for the treatment of colorectal cancer. J Clin Pharm Ther. 2007, 32: 1-14. 10.1111/j.1365-2710.2007.00800.x.
Article
CAS
PubMed
Google Scholar
Schneider Bryan, Sledge George: Drug Insight: VEGF as a therapeutic target for breast cancer. Nature Clinical Practice Oncology. 2007, 4: 181-189. 10.1038/ncponc0740.
Article
CAS
PubMed
Google Scholar
Cabebe E, Fisher GA: Clinical trials of VEGF receptor tyrosine kinase inhibitors in pancreatic ccancer. Expert Opin Investig Drugs. 2007, 16: 467-476. 10.1517/13543784.16.4.467.
Article
CAS
PubMed
Google Scholar
Gridelli C, Maione P, Del Gaizo F, Colantuoni G, Guerriero C, Ferrara C, Nicolella D, Comunale D, De Vita A, Rossi A: Sorafenib and sunitinib in the treatment of advanced non-small cell lung cancer. Oncologist. 2007, 12: 191-200. 10.1634/theoncologist.12-2-191.
Article
CAS
PubMed
Google Scholar
Lovkova M, Ya GN, Buzuk SM, Sokolova NI, Kliment'eva : Chemical Features of Medicinal Plants (Review). Applied Biochemistry and Microbiology. 2001, 37: 229-237. 10.1023/A:1010254131166.
Article
CAS
Google Scholar
Abbas M, Jassbi AR, Zahid M, Ali Z, Alam N, Akhtar F, Iqbal Choudhary M, Ahmad Uddin Viqar: Three new diterpenoids from Euphorbia cheiradenia. Helvetica Chimica Acta. 2000, 83: 2751-2755. 10.1002/1522-2675(20001004)83:10<2751::AID-HLCA2751>3.0.CO;2-B.
Article
CAS
Google Scholar
Schade M, Oschkinat H: NMR fragments screening: tackling protein-protein interaction targets. Curr Opin Drug Discovery Dev. 2005, 8: 365-373.
CAS
Google Scholar
Eyckerman S, Lemmens I, Catteeuw D, Verhee A, Vandekerckhove J, Lievens S, Tavernier : Reverse MAPPIT: screening for protein-protein interaction modifiers in mammalian cells. Nat Methods. 2005, 2: 427-433. 10.1038/nmeth760.
Article
CAS
PubMed
Google Scholar
Choi HJ, Choi YH, Yee SB, Im E, Jung JH, Kim ND: Incinin-1 induces cell cycle arrest and apoptosis in SK-MEL-2 human melanoma cell lines. Mol Carcinog. 2005, 44: 162-173. 10.1002/mc.20084.
Article
CAS
PubMed
Google Scholar
Petit GR, tan R, Cichacz ZA: Antineoplastic agent 542. Isolation and structure of sesterstatin from the Indian Ocean sponge Hyrtios erecta. J Nat Prod. 2005, 68: 1253-1255. 10.1021/np0402221.
Article
Google Scholar
Kirsch G, Kong GM, Wright AD, Kaminsky R: A new bioactive sesterterpene and antiplasmodial alkaloid from the marine sponge hyrtios cf. erecta. J Nat Prod. 2000, 63: 825-829. 10.1021/np990555b.
Article
CAS
PubMed
Google Scholar
Klagsprun M, Folkman J: Peptide growth factors and their receptors. Edited by: Sporn MB, Roberts AB. 1990, Springer, NY, 549-586.
Chapter
Google Scholar
Dunn I, Heese O, Blach P: growth factors in glioma angiogenesis: FGFs, PDGF, EGF and TGFs. J Neuro-Oncol. 2000, 50: 121-137. 10.1023/A:1006436624862.
Article
CAS
Google Scholar
Semino CE, Kamm RD, Lauffenberger DA: Autocrine EGF receptor activation mediates endothelial cell migration and vascular morphogenesis by VEGF under interstitial flow. Exp Cell Res. 2006, 312: 289-298.
CAS
PubMed
Google Scholar
Otrock Z, Makarem J, Shamseddine A: Vascular endothelial growth factor family of ligands and receptors:Review. Bllod cells, Molecules and Diseases. 2007, 38: 258-268. 10.1016/j.bcmd.2006.12.003.
Article
CAS
Google Scholar
Duraisamy Y, Slevin M, Smith N, Bailey J, Zweit J, Smith C, Ahmed N, Gaffney J: Effect of glycation on basic fibroblast growth factor induced angiogenesis and activation of associated signal transduction pathways in vascular endothelial cells: Possible relevance to wound healing. Angiogenesis. 2001, 4: 277-288. 10.1023/A:1016068917266.
Article
CAS
PubMed
Google Scholar
Ifat S, Tamer L, Mink S, Noam A, shivani C, Dietmar S, Dina R: Identification of residues important both for primary receptor binding and specificity in fibroblast growth factor-7. J Biol Chem. 2003, 275: 34881-34886.
Google Scholar
West DC, Thompson WD, Sellls PG, Burbridge MF: Angiogenesis assays using the chick chorioallantoic membrane. In Methods in molecular medicine-Angiogenesis: Reviews and Protocols. Edited by: Murray JC. 2001, Humana Press, 107-130.
Google Scholar