Fig. 1

Matrix representing amino acid substitutions present in RBD domain of SARS-CoV-2 S protein of 31,403 genomes. Name of countries and the number of mutants vs. genomes sampled are given on the Y-axis and the relevant amino acid residues (single letter code) in the reference strain are given on the X-axis. Mutated amino acid residues and their frequency of occurrence are provided in matrix cells. Light green colored matrix cells represent non- interface mutations and dark green color matrix cells represent interface-mutations in the RBD domain of spike protein. Mutations, which are present, at least in two independent genomes at the same position are represented in the matrix along with their positions