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Fig. 1 | BMC Molecular and Cell Biology

Fig. 1

From: CREB1 regulates KPNA2 by inhibiting mir-495-3p transcription to control melanoma progression

Fig. 1

MiR-495-3p was significantly down-regulated in melanoma. A qRT‒PCR detected miR-495-3p levels in melanoma tissues. B Analysis of the relationship between miR-495-3p level and survival of patients with melanoma. C qRT‒PCR detected miR-495-3p levels in melanoma cells, including A375, A2058, B16, and MUM2B cells. HEMa-LP cells served as the negative control. D qRT‒PCR detected miR-495-3p levels after A375 and B16 cells were transfected with miR-495-3p mimics. The mean ± standard deviation represents data from three independent trials (n = 3). *p < 0.05, ** p < 0.01, *** p < 0.001 

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