Butow RA, Avadhani NG: Mitochondrial Signaling: The Retrograde Response. Molecular Cell. 2004, 14 (1): 1-15. 10.1016/S1097-2765(04)00179-0.
Article
CAS
PubMed
Google Scholar
McBride HM, Neuspiel M, Wasiak S: Mitochondria: More Than Just a Powerhouse. Current Biology. 2006, 16 (14): R551-R560. 10.1016/j.cub.2006.06.054.
Article
CAS
PubMed
Google Scholar
Wang C, Youle RJ: The Role of Mitochondria in Apoptosis. Annual review of genetics. 2009
Google Scholar
Passos JF, Simillion C, Hallinan J, Wipat A, von Zglinicki T: Cellular senescence: unravelling complexity. Age Dordrecht, Netherlands. 2009
Google Scholar
Chan SL, Wei Z, Chigurupathi S, Tu W: Compromised respiratory adaptation and thermoregulation in aging and age-related diseases. Ageing research reviews. 2009
Google Scholar
Turner N, Heilbronn LK: Is mitochondrial dysfunction a cause of insulin resistance?. Trends in endocrinology and metabolism: TEM. 2008, 19 (9): 324-330. 10.1016/j.tem.2008.08.001.
Article
CAS
PubMed
Google Scholar
Gogvadze V, Orrenius S, Zhivotovsky B: Mitochondria as targets for chemotherapy. Apoptosis. 2009, 14 (4): 624-640. 10.1007/s10495-009-0323-0.
Article
CAS
PubMed
Google Scholar
Mahad D, Lassmann H, Turnbull D: Review: Mitochondria and disease progression in multiple sclerosis. Neuropathology and applied neurobiology. 2008, 34 (6): 577-589. 10.1111/j.1365-2990.2008.00987.x.
Article
PubMed Central
CAS
PubMed
Google Scholar
Gibson GE, Karuppagounder SS, Shi Q: Oxidant-induced changes in mitochondria and calcium dynamics in the pathophysiology of Alzheimer's disease. Annals of the New York Academy of Sciences. 2008, 1147: 221-232. 10.1196/annals.1427.038.
Article
PubMed Central
CAS
PubMed
Google Scholar
Henchcliffe C, Beal MF: Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis. Nature clinical practice. 2008, 4 (11): 600-609. 10.1038/ncpneuro0924.
Article
CAS
PubMed
Google Scholar
Boveris A, Navarro A: Brain mitochondrial dysfunction in aging. IUBMB life. 2008, 60 (5): 308-314. 10.1002/iub.46.
Article
CAS
PubMed
Google Scholar
Ishii N: Role of oxidative stress from mitochondria on aging and cancer. Cornea. 2007, 26 (9 Suppl 1): S3-9. 10.1097/ICO.0b013e31812f6745.
Article
PubMed
Google Scholar
Orrenius S: Reactive oxygen species in mitochondria-mediated cell death. Drug metabolism reviews. 2007, 39 (2-3): 443-455. 10.1080/03602530701468516.
Article
CAS
PubMed
Google Scholar
Hock MB, Kralli A: Transcriptional control of mitochondrial biogenesis and function. Annual review of physiology. 2009, 71: 177-203. 10.1146/annurev.physiol.010908.163119.
Article
CAS
PubMed
Google Scholar
Ohlmeier S, Kastaniotis AJ, Hiltunen JK, Bergmann U: The Yeast Mitochondrial Proteome, a Study of Fermentative and Respiratory Growth. J Biol Chem. 2004, 279 (6): 3956-3979. 10.1074/jbc.M310160200.
Article
CAS
PubMed
Google Scholar
Hlavata L, Aguilaniu H, Pichova A, Nystrom T: The oncogenic RAS2val19 mutation locks respiration, independently of PKA, in a mode prone to generate ROS. The EMBO journal. 2003, 22 (13): 3337-3345. 10.1093/emboj/cdg314.
Article
PubMed Central
CAS
PubMed
Google Scholar
Hlavata L, Nachin L, Jezek P, Nystrom T: Elevated Ras/protein kinase A activity in Saccharomyces cerevisiae reduces proliferation rate and lifespan by two different reactive oxygen species-dependent routes. Aging cell. 2008, 7 (2): 148-157. 10.1111/j.1474-9726.2007.00361.x.
Article
CAS
PubMed
Google Scholar
Reinders A, Burckert N, Boller T, Wiemken A, De Virgilio C: Saccharomyces cerevisiae cAMP-dependent protein kinase controls entry into stationary phase through the Rim15p protein kinase. Genes & development. 1998, 12 (18): 2943-2955.
Article
CAS
Google Scholar
Toda T, Cameron S, Sass P, Zoller M, Scott J, McCullen B, Hurwitz M, Krebs E, Wigler M: Cloning and characterisation of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae. Molecular and cellular biology. 1987, 7: 1371-1377.
Article
PubMed Central
CAS
PubMed
Google Scholar
Toda T, Cameron S, Sass P, Zoller M, Wigler M: Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase. Cell. 1987, 50: 277-287. 10.1016/0092-8674(87)90223-6.
Article
CAS
PubMed
Google Scholar
Toda T, Uno I, Ishikawa T, Powers S, Kataoka T, Broek D, Cameron S, Broach J, Matsumoto K, Wigler M: In yeast, RAS proteins are controlling elements of adenylate cyclase. Cell. 1985, 40 (1): 27-36. 10.1016/0092-8674(85)90305-8.
Article
CAS
PubMed
Google Scholar
Robertson LS, Causton HC, Young RA, Fink GR: The yeast A kinases differentially regulate iron uptake and respiratory function. Proceedings of the National Academy of Sciences of the United States of America. 2000, 97 (11): 5984-5988. 10.1073/pnas.100113397.
Article
PubMed Central
CAS
PubMed
Google Scholar
Robertson LS, Fink GR: The three yeast A kinases have specific signaling functions in pseudohyphal growth. Proceedings of the National Academy of Sciences of the United States of America. 1998, 95 (23): 13783-13787. 10.1073/pnas.95.23.13783.
Article
PubMed Central
CAS
PubMed
Google Scholar
Akada R, Yamamoto J, Yamashita I: Screening and identification of yeast sequences that cause growth inhibition when overexpressed. Mol Gen Genet. 1997, 254: 267-274. 10.1007/s004380050415.
Article
CAS
PubMed
Google Scholar
Gerst JE, Ferguson K, Vojtek A, Wigler M, Field J: CAP is a bifunctional component of the Saccharomyces cerevisiae adenylyl cyclase complex. Molecular and cellular biology. 1991, 11 (3): 1248-1257.
Article
PubMed Central
CAS
PubMed
Google Scholar
Mintzer KA, Field J: Interactions between adenylyl cyclase, CAP and RAS from Saccharomyces cerevisiae. Cellular signalling. 1994, 6 (6): 681-694. 10.1016/0898-6568(94)90050-7.
Article
CAS
PubMed
Google Scholar
Gourlay CW, Ayscough KR: Actin-Induced Hyperactivation of the Ras Signalling Pathway Leads to Apoptosis in Saccharomyces cerevisiae. Molecular and cellular biology. 2006, 26 (17): 6487-6501. 10.1128/MCB.00117-06.
Article
PubMed Central
CAS
PubMed
Google Scholar
Gourlay CW, Carpp LN, Timpson P, Winder SJ, Ayscough KR: A role for the actin cytoskeleton in cell death and aging in yeast. J Cell Biol. 2004, 164 (6): 803-809. 10.1083/jcb.200310148.
Article
PubMed Central
CAS
PubMed
Google Scholar
Gourlay CW, Ayscough KR: Identification of an upstream regulatory pathway controlling actin-mediated apoptosis in yeast. J Cell Sci. 2005, 118: 2119-2132. 10.1242/jcs.02337.
Article
CAS
PubMed
Google Scholar
Leadsham JE, Miller K, Ayscough KR, Colombo S, Martegani E, Sudbery P, Gourlay CW: Whi2p links nutritional sensing to actin-dependent Ras-cAMP-PKA regulation and apoptosis in yeast. J Cell Sci. 2009, 122: 706-715. 10.1242/jcs.042424.
Article
PubMed Central
CAS
PubMed
Google Scholar
Chevtzoff C, Vallortigara J, Averet N, Rigoulet M, Devin A: The yeast cAMP protein kinase Tpk3p is involved in the regulation of mitochondrial enzymatic content during growth. Biochem Biophys Acta. 2005, 1706: 117-125. 10.1016/j.bbabio.2004.10.001.
CAS
PubMed
Google Scholar
Gueldener U, Heinisch J, Koehler GJ, Voss D, Hegemann JH: A second set of loxP marker cassettes for Cre-mediated multiple gene knockouts in budding yeast. Nucleic acids research. 2002, 30 (6): e23-10.1093/nar/30.6.e23.
Article
PubMed Central
CAS
PubMed
Google Scholar
Mazon MJ, Behrens MM, Morgado E, Portillo F: Low activity of the yeast cAMP-dependent protein kinase catalytic subunit Tpk3 is due to the poor expression of the TPK3 gene. European journal of biochemistry/FEBS. 1993, 213 (1): 501-506. 10.1111/j.1432-1033.1993.tb17787.x.
Article
CAS
PubMed
Google Scholar
Lascaris R, Bussemaker HJ, Boorsma A, Piper M, van der Spek H, Grivell L, Blom J: Hap4p overexpression in glucose-grown Saccharomyces cerevisiae induces cells to enter a novel metabolic state. Genome biology. 2003, 4 (1): R3-10.1186/gb-2002-4-1-r3.
Article
PubMed Central
PubMed
Google Scholar
von der Haar T: Optimized protein extraction for quantitative proteomics of yeasts. PloS one. 2007, 2 (10): e1078-10.1371/journal.pone.0001078.
Article
PubMed Central
PubMed
Google Scholar
Gourlay CW, Carpp LN, Timpson P, Winder SJ, Ayscough KR: A role for the actin cytoskeleton in cell death and aging in yeast. J Cell Biol. 2004, 164 (6): 803-809. 10.1083/jcb.200310148.
Article
PubMed Central
CAS
PubMed
Google Scholar
Westermann B, Neupert W: Mitochondria-targeted green fluorescent proteins: convenient tools for the study of organelle biogenesis in Saccharomyces cerevisiae. Yeast. 2000, 16 (15): 1421-1427. 10.1002/1097-0061(200011)16:15<1421::AID-YEA624>3.0.CO;2-U.
Article
CAS
PubMed
Google Scholar
Wilson RB, Renault G, Jacquet M, Tatchell K: The pde2 gene of Saccharomyces cerevisiae is allelic to rcal and encodes a phosphodiesterase which protects the cell from extracellullar cAMP. FEBS letters. 1993, 325 (3): 191-195. 10.1016/0014-5793(93)81071-7.
Article
CAS
PubMed
Google Scholar
Nagley P, Hall RM, Ooi BG: Amino acid substitutions in mitochondrial ATPase subunit 9 of saccharomyces cerevisiae leading to oligomycin or venturicidin resistance. FEBS letters. 1986, 195 (1-2): 159-163. 10.1016/0014-5793(86)80152-1.
Article
CAS
PubMed
Google Scholar
Cain K, Griffiths DE: Studies of energy-linked reactions. Biochem J. 1977, 162: 575-580.
Article
PubMed Central
CAS
PubMed
Google Scholar
Vachova L, Devaux F, Kucerova H, Ricicova M, Jacq C, Palkova Z: Sok2p transcription factor is involved in adaptive program relevant for long term survival of Saccharomyces cerevisiae colonies. The Journal of biological chemistry. 2004, 279 (36): 37973-37981. 10.1074/jbc.M404594200.
Article
CAS
PubMed
Google Scholar
Vachova L, Palkova Z: Physiological regulation of yeast cell death in multicellular colonies is triggered by ammonia. The Journal of cell biology. 2005, 169 (5): 711-717. 10.1083/jcb.200410064.
Article
PubMed Central
CAS
PubMed
Google Scholar
Garcia-Rodriguez LJ, Gay AC, Pon LA: Puf3p, a Pumilio family RNA binding protein, localizes to mitochondria and regulates mitochondrial biogenesis and motility in budding yeast. The Journal of cell biology. 2007, 176 (2): 197-207. 10.1083/jcb.200606054.
Article
PubMed Central
CAS
PubMed
Google Scholar
Forsburg SL, Guarente L: Identification and characterization of HAP4: a third component of the CCAAT-bound HAP2/HAP3 heteromer. Genes & development. 1989, 3 (8): 1166-1178.
Article
CAS
Google Scholar
Zhang L, Zambon AC, Vranizan K, Pothula K, Conklin BR, Insel PA: Gene expression signatures of cAMP/protein kinase A (PKA)-promoted, mitochondrial-dependent apoptosis. Comparative analysis of wild-type and cAMP-deathless S49 lymphoma cells. The Journal of biological chemistry. 2008, 283 (7): 4304-4313. 10.1074/jbc.M708673200.
Article
CAS
PubMed
Google Scholar
Martinez-Velazquez M, Melendez-Zajgla J, Maldonado V: Apoptosis induced by cAMP requires Smac/DIABLO transcriptional upregulation. Cellular signalling. 2007, 19 (6): 1212-1220. 10.1016/j.cellsig.2007.01.001.
Article
CAS
PubMed
Google Scholar
Pagliarini DJ, Dixon JE: Mitochondrial modulation: reversible phosphorylation takes center stage?. Trends in biochemical sciences. 2006, 31 (1): 26-34. 10.1016/j.tibs.2005.11.005.
Article
CAS
PubMed
Google Scholar
Acin-Perez R, Salazar E, Kamenetsky M, Buck J, Levin LR, Manfredi G: Cyclic AMP produced inside mitochondria regulates oxidative phosphorylation. Cell metabolism. 2009, 9 (3): 265-276. 10.1016/j.cmet.2009.01.012.
Article
PubMed Central
CAS
PubMed
Google Scholar
Cho JH, Lee YK, Chae CB: The modulation of the biological activities of mitochondrial histone Abf2p by yeast PKA and its possible role in the regulation of mitochondrial DNA content during glucose repression. Biochimica et biophysica acta. 2001, 1522 (3): 175-186.
Article
CAS
PubMed
Google Scholar
Sickmann A, Reinders J, Wagner Y, Joppich C, Zahedi R, Meyer HE, Schonfisch B, Perschil I, Chacinska A, Guiard B: The proteome of Saccharomyces cerevisiae mitochondria. Proceedings of the National Academy of Sciences of the United States of America. 2003, 100 (23): 13207-13212. 10.1073/pnas.2135385100.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ward MP, Gimeno CJ, Fink GR, Garrett S: SOK2 may regulate cyclic AMP-dependent protein kinase-stimulated growth and pseudohyphal development by repressing transcription. Molecular and cellular biology. 1995, 15 (12): 6854-6863.
Article
PubMed Central
CAS
PubMed
Google Scholar
Rep M, Proft M, Remize F, Tamas M, Serrano R, Thevelein JM, Hohmann S: The Saccharomyces cerevisiae Sko1p transcription factor mediates HOG pathway-dependent osmotic regulation of a set of genes encoding enzymes implicated in protection from oxidative damage. Molecular microbiology. 2001, 40 (5): 1067-1083. 10.1046/j.1365-2958.2001.02384.x.
Article
CAS
PubMed
Google Scholar
Pascual-Ahuir A, Posas F, Serrano R, Proft M: Multiple levels of control regulate the yeast cAMP-response element-binding protein repressor Sko1p in response to stress. The Journal of biological chemistry. 2001, 276 (40): 37373-37378. 10.1074/jbc.M105755200.
Article
CAS
PubMed
Google Scholar
Lascaris R, Piwowarski J, van der Spek H, Teixeira de Mattos J, Grivell L, Blom J: Overexpression of HAP4 in glucose-derepressed yeast cells reveals respiratory control of glucose-regulated genes. Microbiology (Reading, England). 2004, 150 (Pt 4): 929-934.
Article
CAS
Google Scholar
Nowikovsky K, Reipert S, Devenish RJ, Schweyen RJ: Mdm38 protein depletion causes loss of mitochondrial K+/H+ exchange activity, osmotic swelling and mitophagy. Cell death and differentiation. 2007, 14 (9): 1647-1656. 10.1038/sj.cdd.4402167.
Article
CAS
PubMed
Google Scholar
Barrientos A, Barros MH, Valnot I, Rotig A, Rustin P, Tzagoloff A: Cytochrome oxidase in health and disease. Gene. 2002, 286 (1): 53-63. 10.1016/S0378-1119(01)00803-4.
Article
CAS
PubMed
Google Scholar
Shoubridge EA: Cytochrome c oxidase deficiency. American journal of medical genetics. 2001, 106 (1): 46-52. 10.1002/ajmg.1378.
Article
CAS
PubMed
Google Scholar
Sullivan PG, Brown MR: Mitochondrial aging and dysfunction in Alzheimer's disease. Progress in neuro-psychopharmacology & biological psychiatry. 2005, 29 (3): 407-410.
Article
CAS
Google Scholar