Lin FT, Lane MD: CCAAT/enhancer binding protein alpha is sufficient to initiate the 3T3-L1 adipocyte differentiation program. Proc Natl Acad Sci USA. 1994, 91: 8757-8761.
Brun RP, Tontonoz P, Forman BM, Ellis R, Jasmine C, Evans RM, Spiegelman BM: Differential activation of adipogenesis by multiple PPAR isoforms. Gene Dev. 1996, 10: 974-984.
Francisco JN, Eric N: a transcriptional target for signaling pathways controlling skeletal muscle growth and differentiation. Curr Opinion Cell Biol. 1999, 11: 683-688. 10.1016/S0955-0674(99)00036-8.
Black BL, Olson EN: Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins. Ann Rev Cell Dev Biol. 1998, 14: 167-196. 10.1146/annurev.cellbio.14.1.167.
Tao H, Umek RM: Reciprocal regulation of gadd45 by C/EBP alpha and c-Myc. DNA and Cell Biology. 1999, 18: 75-84. 10.1089/104454999315646.
Constance CM, Morgan JIt, Umek RM: C/EBPalpha regulation of the growth-arrest-associated gene gadd45. Mol Cell Biol. 1996, 16: 3878-3883.
Cha HH, Cram EJ, Wang EC, Huang AJ, Kasler HG, Firestone GL: Glucocorticoids stimulate p21 gene expression by targeting multiple transcriptional elements within a steroid responsive region of the p21waf1/cip1 promoter in rat hepatoma cells. J Biol Chem. 1998, 273: 1998-2007. 10.1074/jbc.273.4.1998.
Ramos RA, Meilandt WJ, Wang EC, Firestone GL: Dysfunctional glucocorticoid receptor with a single point mutation ablates the CCAAT/enhancer binding protein-dependent growth suppression response in a steroid-resistant rat hepatoma cell variant. FASEB J. 1999, 13: 169-180.
Lane MD, Tang QQ, Jiang MS: Role of the CCAAT enhancer binding proteins (CVEBPs) in adipocyte differentiation. Biochem Biophys Res Comm. 1999, 266: 677-683. 10.1006/bbrc.1999.1885.
Nord M, Cassel TN, Braun H, Suske G: Regulation of the Clara cell secretory protein/uteroglobin promoter in lung. Annals NY Acad Scie. 2000, 923: 154-165.
MacDougald OA, Lane MD: Transcriptional regulation of gene expression during adipocyte differentiation. Ann Rev Biochem. 1995, 64: 345-373. 10.1146/annurev.biochem.64.1.345.
Wedel A, Ziegler-Heitbrock HW: The C/EBP family of transcription factors. Immunobiology. 1995, 193: 171-185.
Rangwala SM, Lazar MA: Transcriptional control of adipogenesis. Ann Rev Nutrition. 2000, 20: 535-559. 10.1146/annurev.nutr.20.1.535.
Wu Z, Puigserver P, Spiegelman BM: Transcriptional activation of adipogenesis. Curr Opinion Cell Biol. 1999, 11: 689-694. 10.1016/S0955-0674(99)00037-X.
Darlington GJ: Molecular mechanisms of liver development and differentiation. Curr Opinion Cell Biol. 1999, 11: 678-682. 10.1016/S0955-0674(99)00035-6.
Diehl AM: Roles of CCAAT/enhancer-binding proteins in regulation of liver regenerative growth. J Biol Chem. 1998, 273: 30843-30846. 10.1074/jbc.273.47.30843.
Darlington GJ, Ross SE, MacDougald OA: The role of C/EBP genes in adipocyte differentiation. J Biol Chem. 1998, 273: 30057-30060. 10.1074/jbc.273.46.30057.
McKnight SL: McBindall-A Better Name for CCAAT/Enhancer Binding Proteins?. Cell. 2001, 107: 259-261.
Wang N, Finegold MJ, Bradley A, Ou CN, Abdelsayed SV, Wilde MD, Taylor LR, Wilson DR, Darlington GJ: Imparied energy metabolism in C/EBPalpha knockout mice. Science. 1995, 269: 1108-1112.
Darlington GJ, Wang N, Hanson RW: C/EBP alpha: a critical regulator of genes governing integrative metabolic processes. Curr Opin Genet Dev. 1995, 5: 565-570. 10.1016/0959-437X(95)80024-7.
Flodby P, Barlow C, Kylefjord H, Ahrlund-Richter L, Xanthopoulos KG: Increased hepatic cell proliferation and lung abnormalities in mice deficient in CCAAT/enhancer binding protein alpha. J Biol Chem. 1996, 271: 24753-24760. 10.1074/jbc.271.40.24753.
Timchenko NA, Harris TE, Wilde M, Bilyeu TA, Burgess-Beusse BL, Finegold MJ, Darlington GJ: CCAAT/enhancer binding protein alpha regulates p21 protein and hepatocyte proliferation in newborn mice. Mol Cell Biol. 1997, 17: 7353-7361.
Hendricks-Taylor LR, Darlington GJ: Inhibition of cell proliferation by C/EBP alpha occurs in many cell types, does not require the presence of p53 or Rb, and is not affected by large T-antigen. Nucl Acids Res. 1995, 23: 4726-4733.
Timchenko NA, Wilde M, Nakanishi M, Smith I, Darlington GJ: CCAAT/enhancer-binding protein alpha (C/EBP alpha) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein. Gene Dev. 1996, 10: 804-815.
Harris TE, Albrecht JH, Nakanishi M, Darlington GJ: CCAAT/Enhancer-binding protein-alpha cooperates with p21 to inhibit cyclin-dependent kinase-2 activity and induces growth arrest independent of DNA binding. J Biol Chem. 2001, 276: 29200-29209. 10.1074/jbc.M011587200.
Slomiany BA, D'Arigo KL, Kelly MM, Kurtz DT: C/EBPalpha inhibits cell growth via direct repression of E2F-DP-mediated transcription. Mol Cell Biol. 2000, 20: 5986-5997. 10.1128/MCB.20.16.5986-5997.2000.
Soriano HE, Kang DC, Finegold MJ, Hicks MJ, Wang ND, Harrison W, Darlington GJ: Lack of C/EBP alpha gene expression results in increased DNA synthesis and an increased frequency of immortalization of freshly isolated mice hepatocytes. Hepatology. 1998, 27: 392-401.
Vinson CR, Sigler PB, McKnight SL: Scissors-grip model for DNA recognition by a family of leucine zipper proteins. Science. 1989, 246: 911-916.
Shuman JD, Vinson CR, McKnight SL: Evidence of changes in protease sensitivity and subunit exchange rate on DNA binding by CVEBP. Science. 1990, 249: 771-774.
Pei DQ, Shih CH: An "attenuator domain" is sandwiched by two distinct transactivation domains in the transcription factor C/EBP. Mol Cell Biol. 1991, 11: 1480-1487.
Nerlov C, Ziff EB: CCAAT/enhancer binding protein-alpha amino acid motifs with dual TBP and TFIIB binding ability co-operate to activate transcription in both yeast and mammalian cells. EMBO J. 1995, 14: 4318-4328.
Friedman AD, McKnight SL: Identification of two polypeptide segments of CCAAT/enhancer-binding protein required for transcriptional activation of the serum albumin gene. Gene Dev. 1990, 4: 1416-1426.
Porse BT, Pedersen TA, Xu X, Lindberg B, Wewer UM, Friis-Hansen L, Nerlov C: E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo. Cell. 2001, 107: 247-258.
Timchenko NA, Wilde M, Darlington GJ: C/EBPalpha regulates formation of S-phase-specific E2F-p107 complexes in livers of newborn mice. Mol Cell Biol. 1999, 19: 2936-2945.
Timchenko NA, Wilde M, Iakova P, Albrecht JH, Darlington GJ: E2F/p107 and E2F/p130 complexes are regulated by C/EBPalpha in 3T3-L1 adipocytes. Nucl Acids Res. 1999, 27: 3621-3630. 10.1093/nar/27.17.3621.
Wang H, Iakova P, Wilde M, Welm A, Goode T, Roesler WJ, Timchenko NA: C/EBPalpha arrests cell proliferation through direct Inhibition of Cdk2 and Cdk4. Mol Cell. 2001, 8: 817-828.
Cram EJ, Ramos RA, Wang EC, Cha HH, Nishio Y, Firestone GL: Role of the CCAAT/enhancer binding protein-alpha transcription factor in the glucocorticoid stimulation of the p21waf1/cip1 gene promoter activity in growth-arrested rat hepatoma cells. J Biol Chem. 1998, 273: 2008-2014. 10.1074/jbc.273.4.2008.
Shugart EC, Levenson AS, Constance CM, Umek RM: Differential expression of gas and gadd genes at distinct growth arrest points during adipocyte development. Cell Growth Diff. 1995, 6: 1541-1547.
Tao H, Umek RM: C/EBPalpha is required to maintain postmitotic growth arrest in adipocytes. DNA and Cell Biology. 2000, 19: 9-18. 10.1089/104454900314663.
Müller C, Alunni-Fabbroni M, Kowenz-Leutz E, Mo X, Tommasino M, Leutz A: Separation of C/EBPalpha-mediated proliferation arrest and differentiation pathways. Proc Natl Acad Sci USA. 1999, 96: 7276-7281. 10.1073/pnas.96.13.7276.
Schaufele F, Cassill JA, West BL, Reudelhuber T: Resolution by diagonal gel mobility shift assays of multisubunit complexes binding to a functionally important element of the rat growth hormone gene promoter. J Biol Chem. 1990, 265: 14592-14598.
Schaufele F: CCAAT/enhancer-binding protein alpha activation of the rat growth hormone promoter in pituitary progenitor GHFT1-5 cells. J Biol Chem. 1996, 271: 21484-21489.
Jacob KK, Stanley FM: CCAAT/enhancer-binding protein alpha is a physiological regulator of prolactin gene expression. Endocrinology. 1999, 140: 4542-4550.
Chuang FM, West BL, Baxter JD, Schaufele F: Activities in Pit-1 determine whether receptor interacting protein 140 activates or inhibits Pit-1/nuclear receptor transcriptional synergy. Mol Endocrinol. 1997, 11: 1332-1341.
Schaufele F, Enwright JFI, Wang X, Teoh C, Srihari R, Erickson RL, MacDougald OA, Day RN: CCAAT/enhancer binding protein alpha assembles essential cooperating factors in common subnuclear domains. Mol Endocrinol. 2001, 15: 1665-1676.
Zhang W-H, Srihari R, Day RN, Schaufele F: CCAAT/Enhancer Binding Protein alpha alters histone H3 acetylation at large subnuclear domains. J Biol Chem. 2001, 276: 40373-40376. 10.1074/jbc.C100505200.
Ziogas A, Lorenz IC, Moelling K, Radziwill G: Mitotic Raf-1 is stimulated independently of Ras and is active in the cytoplasm. J Biol Chem. 1998, 273: 24108-24114. 10.1074/jbc.273.37.24108.
Krude T: Mimosine arrests proliferating human cells before onset of DNA replication in a dose-dependent manner. Exp Cell Res. 1999, 247: 148-159. 10.1006/excr.1998.4342.
Tang QQ, Lane MD: Activation and centromeric localization of CCAAT/enhancer-binding proteins during the mitotic clonal expansion of adipocyte differentiation. Gene Dev. 1999, 13: 2231-2241. 10.1101/gad.13.17.2231.
Craig JM, Earnshaw WC, Vagnarelli P: Mammalian centromeres: DNA sequence, protein composition, and role in cell cycle progression. Exp Cell Res. 1999, 246: 249-262. 10.1006/excr.1998.4278.
Skibbens RV, Hieter P: Kinetochores and the checkpoint mechanism that monitors for defects in the chromosome segregation machinery. Ann Rev Gen. 1998, 32: 307-337. 10.1146/annurev.genet.32.1.307.
Lekstrom-Himes J, Xanthopoulos KG: Biological role of the CCAAT/enhancer-binding protein family of transcription factors. J Biol Chem. 1998, 273: 28545-28548. 10.1074/jbc.273.44.28545.
Umek RM, Friedman AD, McKnight SL: CCAAT-enhancer binding protein: A component of a differentiation switch. Science. 1991, 251: 288-292.
Chen PL, Riley DJ, Chen Y, Lee WH: Retionblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs. Gene Dev. 1996, 10: 2794-2804.
Park J-S, Qiao L, Gilfor D, Yang MY, Hylemon PB, Benz C, Darlington G, Firestone G, Fisher PB, Dent P: A role for both Ets and C/EBP transcription factors and mRNA stabilization in the MAPK-dependent increase in p21 Cip-1/WAF-1/mda6 protein levels in primary hepatocytes. Mol Biol Cell. 2000, 10: 2915-2932.
Ramos RA, Nishio Y, Maiyar AC, Simon KE, Ridder CC, Ge Y, Firestone GL: Glucocorticoid-stimulated CCAAT/enhancer-binding protein alpha expression is required for steroid-induced G1 cell cycle arrest of minimal-deviation rat hepatoma cells. Mol Cell Biol. 1996, 16: 5288-5301.
Heim R, Tsien RY: Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer. Curr Biol. 1996, 6: 178-182.
Day RN: Visualization of Pit-1 transcription factor interactions in the living cell nucleus by fluorescence resonance energy transfer microscopy. Mol Endocrinol. 1998, 12: 1410-1419.
Day RN, Day KH: Specific repression of rat prolactin gene expression in transplanted tumor cells. Mol Endocrinol. 1994, 8: 12-20.