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  1. Autophagy and pyroptosis of macrophages play important protective or detrimental roles in sepsis. However, the underlying mechanisms remain unclear. High mobility group box protein 1 (HMGB1) is associated with...

    Authors: Jiawei Shang, Feng Zhao, Yongmei Cao, Feng Ping, Wei Wang and Yingchuan Li
    Citation: BMC Molecular and Cell Biology 2023 24:2
  2. Tendon injury is associated with oxidative stress, leading to reactive oxygen species (ROS) production and inflammation. N-acetyl-L-cysteine (NAC) is a potent antioxidant. However, how NAC affects the biologic...

    Authors: Kang Lu, Mei Zhou, Liyuan Wang, Yang Wang, Hong Tang, Gang He, Huan Wang, Chuyue Tang, Jie He, Wei Wang, Kanglai Tang, Yunjiao Wang and Zhongliang Deng
    Citation: BMC Molecular and Cell Biology 2023 24:1
  3. Considering the high correlation between the functional decline in Alzheimer’s disease (AD) and the propagation of aggregated tau protein, many research efforts are focused on determining the underlying molecu...

    Authors: Andreia Ferreira, Ines Royaux, Jian Liu, Zhangjie Wang, Guowei Su, Diederik Moechars, Nico Callewaert and Louis De Muynck
    Citation: BMC Molecular and Cell Biology 2022 23:61
  4. Cold inducible RNA-binding protein (CIRP) is a key protein in the hypothermic therapy. Highly expressed CIRP exerts a neuroprotective effect on neurons. The aim of this study is to provide the evidence of the ...

    Authors: Aijun Liu, Shouchun Li, Yongcheng Jiao, Haibo Kong and Zhiwen Zhang
    Citation: BMC Molecular and Cell Biology 2022 23:58
  5. Magnolia, a traditional and important ornamental plant in urban greening, has been cultivated for about 2000 years in China for its elegant flower shape and gorgeous flower color. Most varieties of Magnolia bloom...

    Authors: Lingjuan Xuan, Qianqian Wang, Zhigao Liu, Bin Xu, Shaoyu Cheng, Yingjia Zhang, Danying Lu, Bin Dong, Dongmei Zhang, Lang Zhang, Jingjing Ma and Yamei Shen
    Citation: BMC Molecular and Cell Biology 2022 23:56
  6. Doxorubicin (DOX), which is widely used in cancer treatment, can induce cardiomyopathy. One of the main mechanisms whereby DOX induces cardiotoxicity involves pyroptosis through the NLR family pyrin domain con...

    Authors: Soyoung Hwang, Se-Hee Kim, Kwai Han Yoo, Myung-Hee Chung, Jin Woo Lee and Kuk Hui Son
    Citation: BMC Molecular and Cell Biology 2022 23:55
  7. Pyroptosis of endothelial cells is a new cause of endothelial dysfunction in multiple diseases. Ceramide acts as a potential bioactive mediator of inflammation and increases vascular endothelial permeability i...

    Authors: Fangfang Liu, Yangyang Zhang, Yining Shi, Kai Xiong, Fugui Wang and Jin Yang
    Citation: BMC Molecular and Cell Biology 2022 23:54
  8. Placement of a cultured synovial mesenchymal stem cell (MSC) suspension on a repaired meniscus for 10 min accelerated meniscus repair. Upon placement of the MSC suspension on the meniscus, microspikes projecti...

    Authors: Shunichi Fujii, Kentaro Endo, Nobutake Ozeki, Yuriko Sakamaki, Yuji Kohno, Mitsuru Mizuno, Hisako Katano, Kunikazu Tsuji, Hideyuki Koga and Ichiro Sekiya
    Citation: BMC Molecular and Cell Biology 2022 23:53
  9. Keloid is a benign proliferative fibrous disease featured by excessive fibroblast proliferation after skin injury. However, the mechanism of abnormal cell proliferation is still unclear. Herein, we investigate...

    Authors: Hanye Liu, Guanghai Yan, Li Li, Dandan Wang, Yu Wang, Shan Jin, Zhehu Jin, Liangchang Li and Lianhua Zhu
    Citation: BMC Molecular and Cell Biology 2022 23:52
  10. To establish castration-resistant prostate cancer (CRPC) - Lncap androgen-independent (AI) cell line from Lncap androgen-dependent (AD) cell line, and explore the different molecular biological between these t...

    Authors: Huifeng Wang, Xihua Wei, Die Zhang, Weidong Li and Yanling Hu
    Citation: BMC Molecular and Cell Biology 2022 23:51
  11. The present study aims to explore the correlation of the transforming growth factor β (TGF-β), drosophila mothers against decapentaplegic protein gene (SMAD) 2/3/4, and leukemia inhibitory factors (LIF) with t...

    Authors: Shuang-li Qin, Yun Guo, Shui-Xue Li, Ling Zhou, Azguli Maimaiti, Yusufu Akemu, Jun He and Hai-Xia Yao
    Citation: BMC Molecular and Cell Biology 2022 23:50
  12. Abnormal expression of ribosomal proteins has an important regulatory effect on the progression of cancer. RPL5 is involved in the progression of various malignancies, however, the role of RPL5 in colon cancer...

    Authors: Huahua Zhang, Junli Liu, Qingqing Dang, Xueru Wang, Jie Chen, Xiaoyin Lin, Na Yang, Juan Du, Haiyan Shi, Yong Liu and Jiming Han
    Citation: BMC Molecular and Cell Biology 2022 23:48
  13. Although hormonal and metabolic dysfunction have been recognized as a possible cause of polycystic ovarian syndrome (PCOS), the associations between hyperandrogenism and aryl hydrocarbon receptor (Ahr) signali...

    Authors: Fatemeh Eini, Maryam Azizi kutenaei, Tahereh Foroutan and Ensieh Salehi
    Citation: BMC Molecular and Cell Biology 2022 23:47
  14. Cholangiocarcinoma is a kind of invasive malignant tumor followed by hepatocellular carcinoma. miR-451 was suggested to function as regulator in various human tumors, but its role in mediating tumor progressio...

    Authors: Dengfang Guo, Qingling Wang, Jiancheng Huang, Zhanglin Hu, Chun Chen, Chun Zhang and Feng Lin
    Citation: BMC Molecular and Cell Biology 2022 23:46
  15. Acetaminophen is commonly recommended for the early analgesia of osteoarthritis. However, the molecular mechanism by which it acts remains unknown. The aim of this study is to investigate the effect of acetami...

    Authors: Jie Gao, Yan Li, Zijin Liu, Dong Wang and Huawu Zhang
    Citation: BMC Molecular and Cell Biology 2022 23:45
  16. Cervical cancer is an important malignant tumor threatening the physical and mental health of women in the world. As a new calcium activated chloride channel protein, calcium activated chloride channel (CLCA2) pl...

    Authors: Wenhu Xin, Jian Zhang, Haibin Zhang, Xueyao Ma, Yunzhong Zhang, Yufeng Li and Fang Wang
    Citation: BMC Molecular and Cell Biology 2022 23:44
  17. The cranial region is a complex set of blood vessels, cartilage, nerves and soft tissues. The reconstruction of cranial defects caused by trauma, congenital defects and surgical procedures presents clinical ch...

    Authors: Yang Liu, Pingping Niu, Mengqi Zhou and Hui Xue
    Citation: BMC Molecular and Cell Biology 2022 23:43
  18. COVID-19 is a disease caused by SARS-CoV-2, which can cause mild to serious infections in humans. We aimed to explore the effect of growth hormone (GH)/estrogen/androgen in normal human lung epithelial BEAS-2B...

    Authors: Zemin Zhu, Zhijian Zhao, Xun Chen, Zhou Chu, Yi He, Yingzheng Tan, Juan Zhou and Caixi Tang
    Citation: BMC Molecular and Cell Biology 2022 23:42
  19. Despite the recent progress in the differentiation strategies of stem cells into pancreatic beta cell lineage, current protocols are not optimized for different cell types. The purpose of this study is to inve...

    Authors: Riham M. Aly, Hadeer A. Aglan, Ghada Nour Eldeen and Hanaa H. Ahmed
    Citation: BMC Molecular and Cell Biology 2022 23:41
  20. Aquaporins are channel proteins, form pores in the membrane of biological cells to facilitate the transcellular and transepithelial water movement. The role of Aquaporins in carcinogenesis has become an area o...

    Authors: Amir Hossein Mansourabadi, Azin Aghamajidi, Fatemeh Faraji, Shirin Taghizadeh, Leila Mohamed Khosroshahi, Mona Bahramkiya and Maryam Azimi
    Citation: BMC Molecular and Cell Biology 2022 23:40
  21. The AAA + ATPase p97 is an essential unfoldase/segragase involved in a multitude of cellular processes. It functions as a molecular machine critical for protein homeostasis, homotypic membrane fusion events an...

    Authors: Abolfazl Mirzadeh, George Kobakhidze, Rémi Vuillemot, Slavica Jonic and Isabelle Rouiller
    Citation: BMC Molecular and Cell Biology 2022 23:39
  22. Glioblastoma (GBM) represents nearly one-half of primary brain tumors, and the median survival of patients with GBM is only 14.6 months. Surgery followed by radiation with concomitant temozolomide (TMZ) therap...

    Authors: Hao Chen, Chunlin Li, Haiyang Hu and Bin Zhang
    Citation: BMC Molecular and Cell Biology 2022 23:38
  23. Endometriosis is one of the most common gynecological diseases, and seriously reduces the quality of life of patients. However, the pathogenesis of this disease is unclear. Therefore, more studies are needed t...

    Authors: Yanan He, J. Wang, Xinyan Jiang, Jianhua Gao, Yan Cheng, Tian Liang, Jun Zhou, Liyuan Sun and Guangmei Zhang
    Citation: BMC Molecular and Cell Biology 2022 23:37
  24. The non-catalytic region of tyrosine kinase (Nck) is an adaptor protein, which is ubiquitously expressed in many types of cells. In T cells, the Nck1 isoform promotes T cell receptor signalling as well as acti...

    Authors: Aussanee Nuiyen, Araya Rattanasri, Piyamaporn Wipa, Sittiruk Roytrakul, Apirath Wangteeraprasert, Sutatip Pongcharoen and Jutaporn Ngoenkam
    Citation: BMC Molecular and Cell Biology 2022 23:36
  25. In the past decade, we have seen the emergence of sequence-based methods to understand chromosome organization. With the confluence of in situ approaches to capture information on looping, topological domains, an...

    Authors: Meng Wang, Benjamin D. Sunkel, William C. Ray and Benjamin Z. Stanton
    Citation: BMC Molecular and Cell Biology 2022 23:35
  26. Dysregulation of ACTA2-AS1 and miR-532-5p and their functions in various cancers have been widely reported. Their potential of serving as biomarkers in triple-negative breast cancer (TNBC) remains unknown. Thi...

    Authors: Yi Peng, Xiaoxi Huang and Hongmei Wang
    Citation: BMC Molecular and Cell Biology 2022 23:34
  27. Intrinsically disordered proteins (IDPs) lack a stable three-dimensional structure under physiological conditions but play crucial roles in many biological processes. Intrinsically disordered proteins perform ...

    Authors: CanZhuang Sun, YongE Feng and GuoLiang Fan
    Citation: BMC Molecular and Cell Biology 2022 23:33
  28. The single-cell platform provided revolutionary way to study cellular biology. Technologically, a sophistic protocol of isolating qualified single cells would be key to deliver to single-cell platform, which r...

    Authors: Manman Gao, Peng Guo, Xizhe Liu, Penghui Zhang, Zhongyuan He, Liru Wen, Shaoyu Liu, Zhiyu Zhou and Weimin Zhu
    Citation: BMC Molecular and Cell Biology 2022 23:32
  29. Many attempts are used to discover mechanisms driving impaired angiogenesis in age-related diseases. Angiogenesis is highly regulated by different signaling pathways. Here, we investigated the angiogenesis pot...

    Authors: Nesa Janamo Berenjabad, Vahid Nejati and Jafar Rezaie
    Citation: BMC Molecular and Cell Biology 2022 23:31
  30. Lubricin, a proteoglycan encoded by the PRG4 gene, is synthesised by superficial zone (SFZ) chondrocytes and synovial cells. It reduces friction between joints and allows smooth sliding of tendons. Although lubri...

    Authors: Takashi Satake, Shingo Komura, Hitomi Aoki, Akihiro Hirakawa, Yuuki Imai and Haruhiko Akiyama
    Citation: BMC Molecular and Cell Biology 2022 23:30
  31. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters the host cell by binding to angiotensin-converting enzyme 2 (ACE2) receptors. ACE2 is expressed on human airway epithelial cells. Increased A...

    Authors: Yoshitaka Wakabayashi, Shin Nakayama, Ai Yamamoto and Takatoshi Kitazawa
    Citation: BMC Molecular and Cell Biology 2022 23:29
  32. In several human cancers, Krüppel-like factor 5 (KLF5), a zinc finger transcription factor, can contribute to both tumor progression or suppression; however, the precise role of KLF5 in nasopharyngeal carcinom...

    Authors: Chien-Han Yuan, Wei-Chi Hsu, A.-Mei Huang, Ben-Chih Yuan, I.-Hung Chen, Chia-An Hsu, Rong-Feng Chen, Yih-Min Chu, Hui-Hui Lin and Hung-Lung Ke
    Citation: BMC Molecular and Cell Biology 2022 23:28
  33. Synechocystis histidine kinase, Sll0474: Hik28, a signal protein in a two-component signal transduction system, plays a critical role in responding to a decrease in growth temperature and is also involved in nit...

    Authors: Pavinee Kurdrid, Rayakorn Yutthanasirikul, Sirilak Saree, Jittisak Senachak, Monpaveekorn Saelee and Apiradee Hongsthong
    Citation: BMC Molecular and Cell Biology 2022 23:27
  34. Tunneling nanotubes (TNTs) are special membrane structures for intercellular communications. Vital cargoes (such as mitochondria) could be delivered from healthy cells to rescue damaged ones through TNTs. The ...

    Authors: Chia-Wei Lee, Chia-Chen Kuo, Chi-Jung Liang, Huei-Jyuan Pan, Chia-Ning Shen and Chau-Hwang Lee
    Citation: BMC Molecular and Cell Biology 2022 23:26
  35. Chaperonin containing TCP1 subunit 3 (CCT3) acts as an oncogene in cancers, whereas its role and underlying mechanisms in lung adenocarcinoma (LUAD) are poorly understood. This study investigated the clinical ...

    Authors: Kun Wang, Jian He, Changling Tu, Hui Xu, Xugang Zhang, Yongchang Lv and Chao Song
    Citation: BMC Molecular and Cell Biology 2022 23:25
  36. Poor decidualization and abnormal autophagy conditions in the endometria of adenomyosis patients have been reported previously. However, the specific regulatory mechanism of decidualization in adenomyosis and ...

    Authors: Jie Mei, Xiaoqiang Sheng, Yuan Yan, Xinyu Cai, Chunxue Zhang, Jiao Tian, Mei Zhang, Jidong Zhou, Huizhi Shan and Chenyang Huang
    Citation: BMC Molecular and Cell Biology 2022 23:24
  37. Signal transducer and activator of transcription 3 (STAT3) is an oncogenic transcription factor that promotes cell proliferation and immunomodulation in untransformed cells and maintains stemness of transforme...

    Authors: Lena Sophie Behrendsen, Priyanka Rajeev Menon, Muhammad Jawad Khan, Anke Gregus, Oliver Wirths, Thomas Meyer and Julia Staab
    Citation: BMC Molecular and Cell Biology 2022 23:23
  38. Augmentation of oxidative stress after estrogen deficiency leading to functional deficiency of jawbone bone marrow mesenchymal stem cells (BMSCs) causes jawbone loss in osteoporosis. OSGIN2, an oxidative stres...

    Authors: Yi Shuai, Bingyao Liu, Liang Rong, Bingyi Shao, Bo Chen and Lei Jin
    Citation: BMC Molecular and Cell Biology 2022 23:22
  39. Hepatocellular carcinoma (HCC) is a common malignancy. Long non-coding RNAs (lncRNAs) partake in the progression of HCC. However, the role of lncRNA MAPKAPK5-AS1 in the development of HCC has not been fully cl...

    Authors: Zongqing Peng, Xinhua Ouyang, Yexing Wang and Qiming Fan
    Citation: BMC Molecular and Cell Biology 2022 23:21
  40. This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/1471-2091-13-25.

    Authors: Yuejin Li, Na Liu, Damao Huang, Zhenlin Zhang, Zhengke Peng, Chaojun Duan, Xiaowei Tang, Gongjun Tan, Guangrong Yan, Wenhua Mei and Faqing Tang
    Citation: BMC Molecular and Cell Biology 2022 23:20
  41. Triple-negative breast cancer (TNBC) is the most severe type of breast cancer owing to its high heterogeneity, aggressiveness and lack of treatment. Studies have reported that uncarboxylated osteocalcin (GluOC...

    Authors: Jiaojiao Xu, Luyao Ma, Danqing Wang and Jianhong Yang
    Citation: BMC Molecular and Cell Biology 2022 23:18
  42. We have previously found that, in the pathogenic yeast Candida albicans, 18S and 25S ribosomal RNA components, containing more than one phosphate on their 5′-end were resistant to 5′-monophosphate requiring 5′ → ...

    Authors: Miguel A. Rocha, Bhavani S. Gowda and Jacob Fleischmann
    Citation: BMC Molecular and Cell Biology 2022 23:17
  43. Besides controlling the expression of peripheral tissue antigens, the autoimmune regulator (AIRE) gene also regulates the expression of adhesion genes in medullary thymic epithelial cells (mTECs), an essential pr...

    Authors: Ana Carolina Monteleone-Cassiano, Janaina A. Dernowsek, Romario S. Mascarenhas, Amanda Freire Assis, Dimitrius Pitol, Natalia Chermont Santos Moreira, Elza Tiemi Sakamoto-Hojo, João Paulo Mardegan Issa, Eduardo A. Donadi and Geraldo Aleixo Passos
    Citation: BMC Molecular and Cell Biology 2022 23:15

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