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  1. Viruses are obligate intracellular parasites and rely upon the host cell for different steps in their life cycles. The characterization of cellular genes required for virus infection and/or cell killing will b...

    Authors: Jinsong Sheng, Edward L Organ, Chuanming Hao, K Sam Wells, H Earl Ruley and Donald H Rubin

    Citation: BMC Cell Biology 2004 5:32

    Content type: Research article

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  2. The guanine nucleotide exchange factor C3G (RapGEF1) along with its effector proteins participates in signaling pathways that regulate eukaryotic cell proliferation, adhesion, apoptosis and embryonic developme...

    Authors: Vegesna Radha, Ajumeera Rajanna and Ghanshyam Swarup

    Citation: BMC Cell Biology 2004 5:31

    Content type: Research article

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  3. Vacuolar H+-ATPases are large protein complexes of more than 700 kDa that acidify endomembrane compartments and are part of the secretory system of eukaryotic cells. They are built from 14 different (VHA)-subunit...

    Authors: Christoph Kluge, Thorsten Seidel, Susanne Bolte, Shanti S Sharma, Miriam Hanitzsch, Beatrice Satiat-Jeunemaitre, Joachim Roß, Markus Sauer, Dortje Golldack and Karl-Josef Dietz

    Citation: BMC Cell Biology 2004 5:29

    Content type: Research article

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  4. The calcium activated protein phosphatase 2B, also known as calcineurin, has been implicated as a cell signaling molecule involved with transduction of physiological signals (free cytosolic Ca2+) into molecular s...

    Authors: Robert J Talmadge, Jeffrey S Otis, Matthew R Rittler, Nicole D Garcia, Shelly R Spencer, Simon J Lees and Francisco J Naya

    Citation: BMC Cell Biology 2004 5:28

    Content type: Research article

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  5. The dual specificity phosphatase Cdc14 has been shown to be a critical regulator of late mitotic events in several eukaryotes, including S. cerevisiae, S. pombe. C. elegans and H. sapiens. However, Cdc14 homologs...

    Authors: Brett K Kaiser, Maxence V Nachury, Bryan E Gardner and Peter K Jackson

    Citation: BMC Cell Biology 2004 5:27

    Content type: Research article

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  6. Apoptotic cell death plays an essential part in embryogenesis, development and maintenance of tissue homeostasis in metazoan animals. The culmination of apoptosis in vivo is the phagocytosis of cellular corpses. ...

    Authors: Mihai Cikala, Olga Alexandrova, Charles N David, Matthias Pröschel, Beate Stiening, Patrick Cramer and Angelika Böttger

    Citation: BMC Cell Biology 2004 5:26

    Content type: Research article

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  7. We investigated how the synthesis of cAMP, stimulated by isoproterenol acting through β-adrenoreceptors and Gs, is strongly amplified by simultaneous incubation with baclofen. Baclofen is an agonist of δ-aminobut...

    Authors: Alain Robichon, Sylvette Tinette, Cédric Courtial and Franck Pelletier

    Citation: BMC Cell Biology 2004 5:25

    Content type: Research article

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  8. The transport of intra-cellular particles by microtubules is a major biological function. Under appropriate in vitro conditions, microtubule preparations behave as a 'complex' system and show 'emergent' phenomena...

    Authors: Nicolas Glade, Jacques Demongeot and James Tabony

    Citation: BMC Cell Biology 2004 5:23

    Content type: Research article

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  9. The peptidyl-prolyl isomerase Pin1 recently revealed itself as a new player in the regulation of protein function by phosphorylation. Pin1 isomerizes the peptide bond of specific phosphorylated serine or threo...

    Authors: Alexandra L Albert, Sébastien B Lavoie and Michel Vincent

    Citation: BMC Cell Biology 2004 5:22

    Content type: Research article

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  10. Cytochalasin B does not directly activate the oxygen-radical-producing NADPH oxidase activity of neutrophils but transfers desensitized G-protein coupled receptors (GPCR) into an active signaling state by unco...

    Authors: Johan Bylund, Sara Pellmé, Huamei Fu, Ulf-Henrik Mellqvist, Kristoffer Hellstrand, Anna Karlsson and Claes Dahlgren

    Citation: BMC Cell Biology 2004 5:21

    Content type: Research article

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  11. The Transforming Growth Factor-β (TGF-β) regulates myriad cellular events by signaling through members of the Smad family signal transducers. As a key signal transducer of TGF-β, Smad3 exhibits the property of...

    Authors: Claire Nourry, Lola Maksumova, Mona Pang, Xiaohong Liu and Tongwen Wang

    Citation: BMC Cell Biology 2004 5:20

    Content type: Research article

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  12. Gelsolin, an actin capping protein of osteoclast podosomes, has a unique function in regulating assembly and disassembly of the podosome actin filament. Previously, we have reported that osteopontin (OPN) bind...

    Authors: Rajat S Biswas, De Anna Baker, Keith A Hruska and Meenakshi A Chellaiah

    Citation: BMC Cell Biology 2004 5:19

    Content type: Research article

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  13. Golgins are coiled-coil proteins associated with the Golgi apparatus, that are believed to be involved in the tethering of vesicles and the stacking of cisternae, as well as other functions such as cytoskeleta...

    Authors: Yael Fridmann-Sirkis, Symeon Siniossoglou and Hugh RB Pelham

    Citation: BMC Cell Biology 2004 5:18

    Content type: Research article

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  14. Projectin is a giant modular protein of Drosophila muscles and a key component of the elastic connecting filaments (C-filaments), which are involved in stretch activation in insect Indirect Flight Muscles. It is ...

    Authors: Agnes Ayme-Southgate, Christophe Bounaix, Theresa E Riebe and Richard Southgate

    Citation: BMC Cell Biology 2004 5:17

    Content type: Research article

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  15. The mannose 6-phosphate/insulin-like growth factor-II receptor (M6P/IGF2R) is a multi-functional protein that has been implicated in regulation of cell growth and apoptosis. Cardiac myocytes express relatively...

    Authors: Zhihong Chen, Yinlin Ge and Jing X Kang

    Citation: BMC Cell Biology 2004 5:15

    Content type: Research article

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  16. It is known that "second-hand" cigarette smoke leads to abnormal tissue repair and remodelling but the cellular mechanisms involved in these adverse effects are not well understood. Fibroblasts play a major ro...

    Authors: Lina S Wong, Harry Miguel Green, Jo Ellen Feugate, Madhav Yadav, Eugene A Nothnagel and Manuela Martins-Green

    Citation: BMC Cell Biology 2004 5:13

    Content type: Research article

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  17. The autosomal dominant form of Emery-Dreifuss muscular dystrophy (AD-EDMD) is caused by mutations in the gene encoding for the lamins A and C (LMNA). Lamins are intermediate filament proteins which form the nu...

    Authors: Beate Reichart, Ruth Klafke, Christine Dreger, Eleonora Krüger, Isabell Motsch, Andrea Ewald, Jochen Schäfer, Heinz Reichmann, Clemens R Müller and Marie-Christine Dabauvalle

    Citation: BMC Cell Biology 2004 5:12

    Content type: Research article

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  18. α1-antitrypsin (AAT) is one of the major serine proteinase inhibitors controlling proteinases in many biological pathways. There is increasing evidence that AAT is able to exert other than antiproteolytic effe...

    Authors: Ruta Aldonyte, Lennart Jansson and Sabina Janciauskiene

    Citation: BMC Cell Biology 2004 5:11

    Content type: Research article

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  19. Opitz G/BBB syndrome is a genetic disorder characterized by developmental midline abnormalities, such as hypertelorism, cleft palate, and hypospadias. The gene responsible for the X-linked form of this disease, M...

    Authors: Caterina Berti, Bianca Fontanella, Rosa Ferrentino and Germana Meroni

    Citation: BMC Cell Biology 2004 5:9

    Content type: Research article

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  20. "Protein-trap" is a method that allows epitope-tagging of endogenous proteins. This method allows for the identification of endogenously expressed proteins that exhibit specific localization of interest. This ...

    Authors: Olga O Sineshchekova, Toshimitsu Kawate, Oleksandr V Vdovychenko and Thomas N Sato

    Citation: BMC Cell Biology 2004 5:8

    Content type: Methodology article

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  21. Transfection agents comprised of cationic lipid preparations are widely used to transfect cell lines in culture with specific recombinant complementary DNA molecules. We have found that cells in culture are of...

    Authors: Camilla Pramfalk, Johanna Lanner, Monica Andersson, Eva Danielsson, Christina Kaiser, Ing-Marie Renström, Malin Warolén and Stephen R James

    Citation: BMC Cell Biology 2004 5:7

    Content type: Research article

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  22. Published work suggests that some types of endothelial cells undergo apoptosis in response to ligation of the receptor Fas (CD95, APO1) but other types are resistant. Because heterogeneity among endothelial ce...

    Authors: Gerasimos Filippatos, Edmund Ang, Claudia Gidea, Erhan Dincer, Rongqi Wang and Bruce D Uhal

    Citation: BMC Cell Biology 2004 5:6

    Content type: Research article

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  23. Phenylephrine (PHE), an α1 adrenergic receptor agonist, increases phospholipase D (PLD) activity, independent of classical and novel protein kinase C (PKC) isoforms, in rat-1 fibroblasts expressing α1A adrenergic...

    Authors: Jean-Hugues Parmentier, Gautam K Gandhi, Monique T Wiggins, Abdelwahab E Saeed, Sylvain G Bourgoin and Kafait U Malik

    Citation: BMC Cell Biology 2004 5:4

    Content type: Research article

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  24. Transforming growth factor-βs (TGF-βs), bone morphogenetic proteins (BMPs) and activins are important regulators of developmental cell growth and differentiation. Signaling by these factors is mediated chiefly...

    Authors: Nieves Ibarrola, Irina Kratchmarova, Daisuke Nakajima, William P Schiemann, Aristidis Moustakas, Akhilesh Pandey and Matthias Mann

    Citation: BMC Cell Biology 2004 5:2

    Content type: Research article

    Published on:

  25. Upon serial passaging of mouse skeletal muscle cells, a small number of cells will spontaneously develop the ability to proliferate indefinitely while retaining the ability to differentiate into multinucleate ...

    Authors: Jonathan A Nowak, Jonathan Malowitz, Mahasweta Girgenrath, Christine A Kostek, Amanda J Kravetz, Janice A Dominov and Jeffrey Boone Miller

    Citation: BMC Cell Biology 2004 5:1

    Content type: Research article

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  26. In Arabidopsis thaliana, the gene Tousled encodes a protein kinase of unknown function, but mutations in the gene lead to flowering and leaf morphology defects. We have recently cloned a mammalian Tousled-L ike K

    Authors: Gulshan Sunavala-Dossabhoy, Yuan Li, Briana Williams and Arrigo De Benedetti

    Citation: BMC Cell Biology 2003 4:16

    Content type: Research article

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  27. Apoptosis occurs frequently for blastocysts cultured in vitro, where conditions are suboptimal to those found in the natural environment. Insulin-like growth factor-1 (IGF-1) plays an important role in preventing...

    Authors: Ta-Chin Lin, Jui-Mei Yen, Kun-Bing Gong, Teng-Tsao Hsu and Lih-Ren Chen

    Citation: BMC Cell Biology 2003 4:14

    Content type: Research article

    Published on:

  28. Phospholipase D (PLD) is involved in many signaling pathways. In most systems, the activity of PLD is primarily regulated by the members of the ADP-Ribosylation Factor (ARF) family of GTPases, but the mechanis...

    Authors: Hai-Sheng Li, Kuntala Shome, Raúl Rojas, Mark A Rizzo, Chandrasekaran Vasudevan, Eric Fluharty, Lorraine C Santy, James E Casanova and Guillermo Romero

    Citation: BMC Cell Biology 2003 4:13

    Content type: Research article

    Published on:

  29. Previously we cloned the human MNB/DYRK1A gene from the "Down syndrome critical region" on chromosome 21. This gene encodes a dual specificity protein kinase that catalyzes its autophosphorylation on serine/threo...

    Authors: Eishi Funakoshi, Takamitsu Hori, Tokuko Haraguchi, Yasushi Hiraoka, Jun Kudoh, Nobuyoshi Shimizu and Fumiaki Ito

    Citation: BMC Cell Biology 2003 4:12

    Content type: Research article

    Published on:

  30. The progression of normal cells through the cell cycle is meticulously regulated by checkpoints guaranteeing the exact replication of the genome during S-phase and its equal division at mitosis. A prerequisite...

    Authors: Ulrike Kronenwett, Juan Castro, Uwe J Roblick, Kaoru Fujioka, Carin Östring, Farinaz Faridmoghaddam, Nongnit Laytragoon-Lewin, Bernhard Tribukait and Gert Auer

    Citation: BMC Cell Biology 2003 4:8

    Content type: Research article

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  31. The cytotoxicity and the rejoining of DNA double-strand breaks induced by γ-rays, H2O2 and neocarzinostatin, were investigated in normal and PARP-1 knockout mouse 3T3 fibroblasts to determine the role of poly(ADP...

    Authors: Georges Noël, Nicole Giocanti, Marie Fernet, Frédérique Mégnin-Chanet and Vincent Favaudon

    Citation: BMC Cell Biology 2003 4:7

    Content type: Research article

    Published on:

  32. Protein Ser/Thr phosphatase 5 (PP5) and its Saccharomyces cerevisiae homolog protein phosphatase T1 (Ppt1p) each contain an N-terminal domain consisting of several tetratricopeptide repeats (TPRs) and a C-termina...

    Authors: Jee-Yeong Jeong, Jeremiah Johns, Christopher Sinclair, Jung-Min Park and Sandra Rossie

    Citation: BMC Cell Biology 2003 4:3

    Content type: Research article

    Published on:

  33. Rho family GTPase regulation of the actin cytoskeleton governs a variety of cell responses. In this report, we have analyzed the role of the GTPase Rho in maintenance of the T lymphocyte actin cytoskeleton.

    Authors: Darren G Woodside, David K Wooten, T Kent Teague, Yuko J Miyamoto, Eva G Caudell, Taturo Udagawa, Bernard F Andruss and Bradley W McIntyre

    Citation: BMC Cell Biology 2003 4:2

    Content type: Research article

    Published on:

  34. Constitutive photomorphogenic 1 (COP1) has been defined as a central regulator of photomorphogenic development in plants, which targets key transcription factors for proteasome-dependent degradation. Although ...

    Authors: Chunling Yi, Haiyang Wang, Ning Wei and Xing Wang Deng

    Citation: BMC Cell Biology 2002 3:30

    Content type: Research article

    Published on:

2018 Journal Metrics

  • Citation Impact

    3.485 - 2-year Impact Factor
    3.227 - 5-year Impact Factor
    0.857 - Source Normalized Impact per Paper (SNIP)
    1.403 - SCImago Journal Rank (SJR)

    Usage 
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