Rakic P: Neuronal migration and contact guidance in the primate telencephalon. Postgrad Med J. 1978, 54: 25-40.
PubMed
Google Scholar
Lu B, Jan L, Jan YN: Control of cell divisions in the central nervous system: symmetry and asymmetry. Ann Rev Neurosci. 2000, 23: 531-556. 10.1146/annurev.neuro.23.1.531.
Article
CAS
PubMed
Google Scholar
Chenn A, McConnell SK: Cleavage orientation and the asymmetric inheritance of Notch1 immunoreactivity in mammalian neurogenesis. Cell. 1995, 82: 631-641. 10.1016/0092-8674(95)90035-7.
Article
CAS
PubMed
Google Scholar
Aicardi J: Malformations of the central nervous system. Diseases of the nervous system in childhood. 1998, Mac Keith, London, 90-91. 2
Google Scholar
Bond J, Roberts E, Mochida GH, Hampshire DJ, Scott S, Askham JM, Springell K, Mahadevan M, Crow YJ, Markham AF, Walsh CA, Woods CG: ASPM is a major determinant of cerebral cortical size. Nat Genet. 2002, 32: 316-320. 10.1038/ng995.
Article
CAS
PubMed
Google Scholar
Hung LY, Tang CJ, Tang TK: Protein 4.1 R-135 interacts with a novel centrosomal protein (CPAP) which is associated with the gamma-tubulin complex. Mol Cell Biol. 2000, 20: 7813-7825. 10.1128/MCB.20.20.7813-7825.2000.
Article
PubMed Central
CAS
PubMed
Google Scholar
Jackson AP, Eastwood H, Bell SM, Adu J, Toomes C, Carr IM, Roberts E, Hampshire DJ, Crow YJ, Mighell AJ, Karbani G, Jafri H, Rashid Y, Mueller RF, Markham AF, Woods CG: Identification of microcephalin, a protein implicated in determining the size of the human brain. Am J Hum Genet. 2002, 71: 136-142. 10.1086/341283.
Article
PubMed Central
CAS
PubMed
Google Scholar
Kouprina N, Pavlicek A, Collins NK, Nakano M, Noskov VN, Ohzeki J, Mochida GH, Risinger JI, Goldsmith P, Gunsior M: The microcephaly ASPM gene is expressed in proliferating tissues and encodes for a mitotic spindle protein. Hum Mol Genet. 2005, 14: 2155-2165. 10.1093/hmg/ddi220.
Article
CAS
PubMed
Google Scholar
Bond J, Roberts E, Springell K, Lizarraga SB, Scott S, Higgins J, Hampshire DJ, Morrison EE, Leal GF, Silva EO, Costa SM, Baralle D, Raponi M, Karbani G, Rashid Y, Jafri H, Bennett C, Corry P, Walsh CA, Woods CG: A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size. Nat Genet. 2005, 37: 353-355. 10.1038/ng1539.
Article
CAS
PubMed
Google Scholar
Alderton GK, Galbiati L, Griffith E, Surinya KH, Neitzel H, Jackson AP, Jeggo PA, O'Driscoll M: Regulation of mitotic entry by microcephalin and its overlap with ATR signalling. Nat Cell Biol. 2006, 8: 725-733. 10.1038/ncb1431.
Article
CAS
PubMed
Google Scholar
Wood JL, Singh N, Mer G, Chen J: MCPH1 functions in an H2AX-dependent but MDC1-independent pathway in response to DNA damage. J Biol Chem. 2007, 282: 35416-35423. 10.1074/jbc.M705245200.
Article
PubMed Central
CAS
PubMed
Google Scholar
Jeffers LJ, Coull BJ, Stack SJ, Morrison CG: Distinct BRCT domains in Mcph1/Brit1 mediate ionizing radiation-induced focus formation and centrosomal localization. Oncogene. 2008, 27: 139-144. 10.1038/sj.onc.1210595.
Article
CAS
PubMed
Google Scholar
Kumar A, Girimaji SC, Duvvari MR, Blanton SH: Mutations in STIL, Encoding a Pericentriolar and Centrosomal Protein, cause Primary Microcephaly. Am J Hum Genet. 2009, 84: 286-290. 10.1016/j.ajhg.2009.01.017.
Article
PubMed Central
CAS
PubMed
Google Scholar
Roberts E, Hampshire DJ, Pattison L, Springell K, Jafri H, Corry P, Mannon J, Rashid Y, Crow Y, Bond J, Woods CG: Autosomal recessive primary microcephaly: an analysis of locus heterogeneity and phenotypic variation. J Med Genet. 2002, 39: 718-721. 10.1136/jmg.39.10.718.
Article
PubMed Central
CAS
PubMed
Google Scholar
Bond J, Scott S, Hampshire DJ, Springell K, Corry P, Abramowicz MJ, Mochida GH, Hennekam RC, Maher ER, Fryns JP, Alswaid A, Jafri H, Rashid Y, Mubaidin A, Walsh CA, Roberts E, Woods CG: Protein-truncating mutations in ASPM cause variable reduction in brain size. Am J Hum Genet. 2003, 73: 1170-1177. 10.1086/379085.
Article
PubMed Central
CAS
PubMed
Google Scholar
Pattison L, Crow YJ, Deeble VJ, Jackson AP, Jafri H, Rashid Y, Roberts E, Woods CG: A fifth locus for primary autosomal recessive microcephaly maps to chromosome 1q31. Am J Hum Genet. 2000, 67: 1578-1580. 10.1086/316910.
Article
PubMed Central
CAS
PubMed
Google Scholar
Jamieson CR, Fryns JP, Jacobs J, Matthijs G, Abramowicz MJ: Primary autosomal recessive microcephaly: MCPH5 maps to 1q25-q32. Am J Hum Genet. 2000, 67: 1575-1577. 10.1086/316909.
Article
PubMed Central
CAS
PubMed
Google Scholar
Pichon B, Vankerckhove S, Bourrouillou G, Duprez L, Abramowicz MJ: A translocation breakpoint disrupts the ASPM gene in a patient with primary microcephaly. Eur J Hum Genet. 2004, 12: 419-421. 10.1038/sj.ejhg.5201169.
Article
CAS
PubMed
Google Scholar
Kumar A, Blanton SH, Babu M, Markandaya M, Girimaji SC: Genetic analysis of primary microcephaly in Indian families: novel ASPM mutations. Clin Genet. 2004, 66: 341-348. 10.1111/j.1399-0004.2004.00304.x.
Article
CAS
PubMed
Google Scholar
Shen J, Eyaid W, Mochida GH, Al-Moayyad F, Bodell A, Woods CG, Walsh CA: ASPM mutations identified in patients with primary microcephaly and seizures. J Med Genet. 2005, 42: 725-729. 10.1136/jmg.2004.027706.
Article
PubMed Central
CAS
PubMed
Google Scholar
Gul A, Hassan MJ, Mahmood S, Chen W, Rahmani S, Naseer MI, Dellefave L, Muhammad N, Rafiq MA, Ansar M: Genetic studies of autosomal recessive primary microcephaly in 33 Pakistani families: novel sequence variants in ASPM gene. Neurogenetics. 2006, 7: 105-110. 10.1007/s10048-006-0042-4. 2006
Article
CAS
PubMed
Google Scholar
Gul A, Tariq M, Khan MN, Hassan MJ, Ali G, Ahmad W: Novel protein-truncating mutations in the ASPM gene in families with autosomal recessive primary microcephaly. J Neurogenet. 2007, 21: 153-63. 10.1080/01677060701508594.
Article
CAS
PubMed
Google Scholar
Nicholas A, Woods G, Swanson E, Cox J, Karbani G, Malik S, Springell K, Hampshire D, Ahmed M, Bond J, Di Benedetto D, Fichera M, Romano C, Dobyns W: The molecular landscape of ASPM mutations in primary microcephaly. J Med Genet. 2008, 46: 249-53. 10.1136/jmg.2008.062380.
Article
PubMed Central
PubMed
Google Scholar
Cheng J, Maquat LE: Nonsense codons can reduce the abundance of nuclear mRNA without affecting the abundance of pre-mRNA or the half-life of cytoplasmic mRNA. Mol Cell Biol. 1993, 13: 1892-1902.
Article
PubMed Central
CAS
PubMed
Google Scholar
Saunders RDC, Avides MC, Howard T, Gonzalez C, Glover DM: The Drosophila gene abnormal spindle encodes a novel microtubule-associated protein that associates with the polar regions of the mitotic spindle. J Cell Biol. 1997, 137: 881-890. 10.1083/jcb.137.4.881.
Article
PubMed Central
CAS
PubMed
Google Scholar
Craig R, Norbury C: The novel murine calmodulin-binding protein Sha1 disrupts mitotic spindle and replication checkpoint function in fission yeast. J Cell Sci. 1998, 11: 3609-3619.
Google Scholar
Rhoads A, Kenguele H: Expression of IQ-motif genes in human cells and ASPM domain structure. Ethn Dis. 2005, 15: 88-91.
Google Scholar
Ripoll P, Pimpinelli S, Valdivia MM, Avila J: A cell division mutant of Drosophila with a functionally abnormal spindle. Cell. 1985, 198541: 907-912. 10.1016/S0092-8674(85)80071-4.
Article
Google Scholar
Gonzalez C, Saunders RD, Casal J, Molina I, Carmena M, Ripoll P, Glover DM: Mutations at the asp locus of Drosophila lead to multiple free centrosomes in syncytial embryos, but restrict centrosome duplication in larval neuroblasts. J Cell Sci. 1990, 96: 605-616.
PubMed
Google Scholar
Avides MC, Glover DM: Abnormal spindle protein, Asp, and the integrity of mitotic centrosomal microtubule organizing centers. Science. 1999, 283: 1733-1735. 10.1126/science.283.5408.1733.
Article
Google Scholar
Avides MC, Tavares A, Glover DM: Polo kinase and Asp are needed to promote the mitotic organizing activity of centrosomes. Nat Cell Biol. 2001, 3: 421-424. 10.1038/35070110.
Article
Google Scholar
Riparbelli MG, Callaini G, Glover DM, Avides MC: A requirement for the abnormal spindle protein to organise microtubules of the central spindle for cytokinesis in Drosophila. J Cell Sci. 2001, 115: 913-922.
Google Scholar
Wakefield JG, Bonaccorsi S, Gatti M: The Drosophila protein asp is involved in microtubule organization during spindle formation and cytokinesis. J Cell Biol. 2001, 153: 637-647. 10.1083/jcb.153.4.637.
Article
PubMed Central
CAS
PubMed
Google Scholar
Morales-Mulia S, Scholey JM: Spindle pole organization in Drosophila S2 cells by dynein, abnormal spindle protein (Asp), and KLP10A. Mol Biol Cell. 2005, 16: 3176-3186. 10.1091/mbc.E04-12-1110.
Article
PubMed Central
CAS
PubMed
Google Scholar
Fish JL, Kosodo Y, Enard W, Paabo S, Huttner WB: Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells. Proc Natl Acad Sci USA. 2006, 103: 10438-10443. 10.1073/pnas.0604066103.
Article
PubMed Central
CAS
PubMed
Google Scholar
Horvath S, Zhang B, Carlson M, Lu KV, Zhu S, Felciano RM, Laurance MF, Zhao W, Qi S, Chen Z: Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target. Proc Natl Acad Sci USA. 2006, 103: 17402-17407. 10.1073/pnas.0608396103.
Article
PubMed Central
CAS
PubMed
Google Scholar
Zhong X, Liu L, Zhao A, Pfeifer GP, Xu X: The abnormal spindle-like, microcephaly-associated (ASPM) gene encodes a centrosomal protein. Cell Cycle. 2005, 4: 1227-1229. 10.4161/cc.4.9.2029.
Article
CAS
PubMed
Google Scholar
Paramasivam M, Chang YJ, LoTurco JJ: ASPM and citron kinase co-localize to the midbody ring during cytokinesis. Cell Cycle I. 2007, 6: 1605-1612. 10.4161/cc.6.13.4356.
Article
CAS
Google Scholar
Tirnauer JS, Bierer BE: EB1 proteins regulate microtubule dynamics, cell polarity, and chromosome stability. J Cell Biol. 2000, 149: 761-766. 10.1083/jcb.149.4.761.
Article
PubMed Central
CAS
PubMed
Google Scholar
Morrison EE: Action and interactions at microtubule ends. Cell Mol Life Sci. 2007, 64: 307-317. 10.1007/s00018-007-6360-3.
Article
CAS
PubMed
Google Scholar
Stepanova T, Slemmer J, Hoogenraad CC, Lansbergen G, Dortland B, De Zeeuw CI, Grosveld F, van Cappellen G, Akhmanova A, Galjart N: Visualisation of microtubule growth in cultured neurons via the use of EB3-GFP (end-binding protein 3-green fluorescent protein). J Neuroscience. 2003, 23: 2655-2664.
CAS
PubMed
Google Scholar
Neumann B, Walter T, Hériché JK, Bulkescher J, Erfle H, Conrad C, Rogers P, Poser I, Held M, Liebel U, Cetin C, Sieckmann F, Pau G, Kabbe R, Wünsche A, Satagopam V, Schmitz MH, Chapuis C, Gerlich DW, Schneider R, Eils R, Huber W, Peters JM, Hyman AA, Durbin R, Pepperkok R, Ellenberg J: Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Nature. 2010, 464: 721-7. 10.1038/nature08869.
Article
PubMed Central
CAS
PubMed
Google Scholar
Fish JL, Dehay C, Kennedy H, Huttner WB: Making bigger brains - the evolution of neural-progenitor-cell division. J Cell Sci. 2008, 121: 2783-2793. 10.1242/jcs.023465.
Article
CAS
PubMed
Google Scholar
Rappaport R: Geometrical relations of the cleavage stimulus in invertebrate eggs. J Theor Biol. 1965, 9: 51-66. 10.1016/0022-5193(65)90056-1.
Article
CAS
PubMed
Google Scholar
White JG, Borisy GG: On the mechanisms of cytokinesis in animal cells. J Theor Biol. 1983, 101: 289-316. 10.1016/0022-5193(83)90342-9.
Article
CAS
PubMed
Google Scholar
D'Avino PP, Savoian MS, Glover DM: Cleavage furrow formation and ingression during animal cytokinesis: a microtubule legacy. J Cell Sci. 2005, 118: 1549-1558. 10.1242/jcs.02335.
Article
PubMed
Google Scholar
Bringmann H, Hyman AA: A cytokinesis furrow is positioned by two consecutive signals. Nature. 2005, 436: 731-734. 10.1038/nature03823.
Article
CAS
PubMed
Google Scholar
Morrison EE, Wardleworth BN, Askham JM, Markham AF, Meredith DM: EB1, a protein which interacts with the APC tumour suppressor, is associated with the microtubule cytoskeleton throughout the cell cycle. Oncogene. 1998, 17: 3471-3477. 10.1038/sj.onc.1202247.
Article
CAS
PubMed
Google Scholar
Askham JM, Moncur PM, Markham AF, Morrison EE: Regulation and function of the interaction between the APC tumour suppressor protein and EB1. Oncogene. 2000, 19: 1950-1958. 10.1038/sj.onc.1203498.
Article
CAS
PubMed
Google Scholar
Langford KJ, Lee T, Adams M, Askham JM, Morrison EE: Examination of actin and microtubule dependent APC localisations in living mammalian cells. BMC Cell Biology. 2006, 7: 3-10.1186/1471-2121-7-3.
Article
PubMed Central
PubMed
Google Scholar
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T: Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 2001, 411: 494-498. 10.1038/35078107.
Article
CAS
PubMed
Google Scholar