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  1. Claudins are key integral proteins of the tight junction. Although they play an essential role in controlling paracellular diffusion in epithelia, increasing evidence supports a role for these proteins in non-...

    Authors: Patricia G Webb, Monique A Spillman and Heidi K Baumgartner

    Citation: BMC Cell Biology 2013 14:19

    Content type: Research article

    Published on:

  2. The objective of this study was to evaluate the effect of bone marrow mesenchymal stem cells (BMSCs) on the apoptosis of granulosa cells (GCs) in rats.

    Authors: Jun-qi Guo, Xia Gao, Zhi-jie Lin, Wei-zhen Wu, Liang-hu Huang, Hui-yue Dong, Jin Chen, Jun Lu, Yun-fen Fu, Jin Wang, Yu-jie Ma, Xiao-wen Chen, Zhi-xian Wu, Fu-qiang He, Shun-liang Yang, Lian-ming Liao…

    Citation: BMC Cell Biology 2013 14:18

    Content type: Research article

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  3. Fibroblasts play a critical role in tumorigenesis, tumor progression and metastasis. However, their detailed molecular characteristics and clinical significance are still elusive. TAGLN is an actin-binding pro...

    Authors: Beiqin Yu, Xuehua Chen, Jianfang Li, Ying Qu, Liping Su, Yibing Peng, Jian Huang, Jun Yan, Yingyan Yu, Qinlong Gu, Zhenggang Zhu and Bingya Liu

    Citation: BMC Cell Biology 2013 14:17

    Content type: Research article

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  4. The kidney-specific NKCC cotransporter isoform NKCC2 is involved in the Na+ reabsorption in the Thich Ascending Limb (TAL) cells and in the regulation of body fluid volume. In contrast, the isoform NKCC1 represen...

    Authors: Monica Carmosino, Federica Rizzo, Silvia Torretta, Giuseppe Procino and Maria Svelto

    Citation: BMC Cell Biology 2013 14:16

    Content type: Methodology article

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  5. Protein Ser/Thr Phosphatase PPP1CC2 is an alternatively spliced isoform of PPP1C that is highly enriched in testis and selectively expressed in sperm. Addition of the phosphatase inhibitor toxins okadaic acid ...

    Authors: Luis Korrodi-Gregório, Mónica Ferreira, Ana Paula Vintém, Wenjuan Wu, Thorsten Muller, Katrin Marcus, Srinivasan Vijayaraghavan, David L Brautigan, Odete A B da Cruz e Silva, Margarida Fardilha and Edgar F da Cruz e Silva

    Citation: BMC Cell Biology 2013 14:15

    Content type: Research article

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  6. Epidermal growth factor receptor (EGFR) is involved in the development of many human malignant tumors and plays an important role in tumor growth and metastasis. Antagonists of EGFR can suppress the growth of ...

    Authors: Yi Huang, Tao Yu, Xiaoyue Fu, Jiao Chen, Ying Liu, Chunjie Li, Yichao Xia, Zhuoyuan Zhang and Longjiang Li

    Citation: BMC Cell Biology 2013 14:13

    Content type: Research article

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  7. The regulatory mechanisms of motor protein-dependent intracellular transport are still not fully understood. The kinesin-1-binding protein, JIP1, can function as an adaptor protein that links kinesin-1 and oth...

    Authors: Tomoko Satake, Karin Otsuki, Yumi Banba, Jun Suenaga, Hisashi Hirano, Yuko Yamanaka, Shigeo Ohno and Syu-ichi Hirai

    Citation: BMC Cell Biology 2013 14:12

    Content type: Research article

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  8. In several species with external fertilization, including frogs, laid unfertilized eggs were found to die by apoptosis outside of the animal body. However, there is no apparent reason for the externally laid e...

    Authors: Sho Iguchi, Tetsushi Iwasaki, Yasuo Fukami and Alexander A Tokmakov

    Citation: BMC Cell Biology 2013 14:11

    Content type: Research article

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  9. The transition of epithelial cells from their normal non-motile state to a motile one requires the coordinated action of a number of small GTPases. We have previously shown that epithelial cell migration is st...

    Authors: Myriam A Attar and Lorraine C Santy

    Citation: BMC Cell Biology 2013 14:9

    Content type: Research article

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  10. The goal of this study was to investigate the anti-angiogenic activity of a novel peptide H-RN, derived from the hepatocyte growth factor kringle 1 domain (HGF K1), in a mouse model of corneal neovascularizati...

    Authors: Ye Sun, Li Su, Zhongxiao Wang, Yi Xu and Xun Xu

    Citation: BMC Cell Biology 2013 14:8

    Content type: Research article

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  11. Cancer stem cells (CSCs) are thought to be capable of surviving conventional chemotherapeutic treatments because the cells have more resistant to anticancer drugs than common cancer cells. Most in vitro studies i...

    Authors: Junsong Chen, Jing Wang, Dengyu Chen, Jie Yang, Cuiping Yang, Yunxia Zhang, Hongyi Zhang and Jun Dou

    Citation: BMC Cell Biology 2013 14:7

    Content type: Research article

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  12. Rap proteins belong to the Ras family of small G-proteins. Dictyostelium RapA is essential and implicated in processes throughout the life cycle. In early development and chemotaxis competent cells RapA induces p...

    Authors: Katarzyna Plak, Douwe Veltman, Fabrizia Fusetti, Jetze Beeksma, Francisco Rivero, Peter JM Van Haastert and Arjan Kortholt

    Citation: BMC Cell Biology 2013 14:6

    Content type: Research article

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  13. The interactions between stem cells and extracellular matrix (ECM) mediated by integrins play important roles in the processes that determine stem cell fate. However, the role of ECM/integrin interaction in th...

    Authors: Di Zeng, Dong-Bo Ou, Ting Wei, Lu Ding, Xiong-Tao Liu, Xin-Lin Hu, Xue Li and Qiang-Sun Zheng

    Citation: BMC Cell Biology 2013 14:5

    Content type: Research article

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  14. Cadmium(Cd), a heavy metal, which has a potent harmful effects, is a highly stress-inducible material that is robustly expressed following disruption of homeostasis in the endoplasmic reticulum (ER) (so-called...

    Authors: Seungwoo Kim, Hyo-Soon Cheon, So-Young Kim, Yong-Sung Juhnn and Young-Youl Kim

    Citation: BMC Cell Biology 2013 14:4

    Content type: Research article

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  15. The mammalian target of rapamycin (mTOR) signalling pathway has a key role in cellular regulation and several diseases. While it is thought that Rheb GTPase regulates mTOR, acting immediately upstream, while r...

    Authors: Rahul B Yadav, Pierre Burgos, Anthony W Parker, Valentina Iadevaia, Christopher G Proud, Rodger A Allen, James P O'Connell, Ananya Jeshtadi, Christopher D Stubbs and Stanley W Botchway

    Citation: BMC Cell Biology 2013 14:3

    Content type: Research article

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  16. Disease manifestations of Staphylococcus aureus are connected to the fibronectin (Fn)-binding capacity of these Gram-positive pathogens. Fn deposition on the surface of S. aureus allows engagement of α5β1 integri...

    Authors: Marina Borisova, Yong Shi, Alexander Buntru, Susanne Wörner, Wolfgang H Ziegler and Christof R Hauck

    Citation: BMC Cell Biology 2013 14:2

    Content type: Research article

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  17. Hyperleptinemia is known to participate in cardiac hypertrophy and hypertension, but the relationship between pressure overload and leptin is poorly understood. We therefore examined the expression of leptin (...

    Authors: Hiroki Matsui, Tomoyuki Yokoyama, Chie Tanaka, Hiroaki Sunaga, Norimichi Koitabashi, Takako Takizawa, Masashi Arai and Masahiko Kurabayashi

    Citation: BMC Cell Biology 2012 13:37

    Content type: Research article

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  18. Telomeres are essential for the maintenance of genomic stability, and telomere dysfunction leads to cellular senescence, carcinogenesis, aging, and age-related diseases in humans. Pigs have become increasingly...

    Authors: Guangzhen Ji, Kai Liu, Maja Okuka, Na Liu and Lin Liu

    Citation: BMC Cell Biology 2012 13:36

    Content type: Research article

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  19. Induced pluripotent stem cells (iPSC) are generated by reprogramming somatic cells into embryonic like state (ESC) using defined factors. There is great interest in these cells because of their potential for a...

    Authors: Feng Li and Christopher Niyibizi

    Citation: BMC Cell Biology 2012 13:35

    Content type: Research article

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  20. Covalent modifications of proteins provide a mechanism to control protein function. Here, we have investigated modifications of the heptameric Sec complex which is responsible for post-translational protein im...

    Authors: Christina Soromani, Naiyan Zeng, Klaus Hollemeyer, Elmar Heinzle, Marie-Christine Klein, Thomas Tretter, Matthew N J Seaman and Karin Römisch

    Citation: BMC Cell Biology 2012 13:34

    Content type: Research article

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  21. Transient receptor potential canonical (TRPC) channels are non-selective cation channels involved in receptor-mediated calcium signaling in diverse cells and tissues. The canonical transient receptor potential...

    Authors: Robert Carrasquillo, Dequan Tian, Sneha Krishna, Martin R Pollak, Anna Greka and Johannes Schlöndorff

    Citation: BMC Cell Biology 2012 13:33

    Content type: Research article

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  22. Nucleolin is a protein over-expressed on the surface of activated cells. Recent studies have underlined the involvement of cell surface nucleolin in angiogenesis processes. This cell surface molecule serves as...

    Authors: Charalampos Birmpas, Jean Paul Briand, Josẻ Courty and Panagiotis Katsoris

    Citation: BMC Cell Biology 2012 13:32

    Content type: Research article

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  23. Mig2 has been described as a transcriptional factor that in the absence of Mig1 protein is required for glucose repression of the SUC2 gene. Recently it has been reported that Mig2 has two different subcellular l...

    Authors: Alejandra Fernández-Cid, Montserrat Vega, Pilar Herrero and Fernando Moreno

    Citation: BMC Cell Biology 2012 13:31

    Content type: Research article

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  24. AmpA is a secreted 24Kd protein that has pleiotropic effects onDictyostelium development. Null mutants delay development atthe mound stage with cells adhering too tightly to the substrate. Prestalkcells initially...

    Authors: Elizabeth F Noratel, Chere’ L Petty, Jessica S Kelsey, Hoa N Cost, Nisha Basappa and Daphne D Blumberg

    Citation: BMC Cell Biology 2012 13:29

    Content type: Research article

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  25. Autophagy is a ubiquitous cellular process responsible for the bulk degradation of cytoplasmic components through the autophagosomal-lysosomal pathway. In skeletal muscle, autophagy has been regarded as a key ...

    Authors: Xiaokun Yu, Junfeng Ma, Feng Lin, Wanke Zhao, Xueqi Fu and Zhizhuang Joe Zhao

    Citation: BMC Cell Biology 2012 13:28

    Content type: Research article

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  26. The Dystrophin Glycoprotein Complex (DGC) is at the center of significant inheritable diseases, such as muscular dystrophies that can be fatal and impair neuronal function in addition to muscle degeneration. R...

    Authors: April K Marrone, Evgeniia V Edeleva, Mariya M Kucherenko, Nai-Hua Hsiao and Halyna R Shcherbata

    Citation: BMC Cell Biology 2012 13:26

    Content type: Research article

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  27. Ovarian cancer is one of the most lethal malignancies in women, as it is frequently detected at an advanced stage, and cancers often become refractory to chemotherapy. Evidence suggests that dysregulation of p...

    Authors: Uttara Saran, Frank Arfuso, Nikolajs Zeps and Arunasalam Dharmarajan

    Citation: BMC Cell Biology 2012 13:25

    Content type: Research article

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  28. One of the problems associated with osteosarcoma is the frequent formation of micrometastases in the lung prior to diagnosis because the development of metastatic lesions often causes a fatal outcome. Therefor...

    Authors: Atsushi Nakamura, Junichi Aizawa, Kenshi Sakayama, Teruki Kidani, Tomoyo Takata, Yoshiaki Norimatsu, Hiromasa Miura and Hiroshi Masuno

    Citation: BMC Cell Biology 2012 13:24

    Content type: Research article

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  29. Ovarian hyper stimulation syndrome (OHSS) is an iatrogenic complication associated with fertility drugs. It is characterized by increased vascular permeability and substantial fluid shift with accumulation in ...

    Authors: Pei-Yin Jin, Yong-Chao Lu, Ling Li and Qin-Fu Han

    Citation: BMC Cell Biology 2012 13:23

    Content type: Research article

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  30. In interferon-γ-stimulated cells, the dimeric transcription factor STAT1 (s ignal t ransducer and a ctivator of t ranscription 1) recognizes semi-palindromic motifs in the promoter regions of cytokine-driven targ...

    Authors: Verena Koch, Julia Staab, Volker Ruppert and Thomas Meyer

    Citation: BMC Cell Biology 2012 13:22

    Content type: Research article

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  31. Adipose tissues contain populations of pluripotent mesenchymal stem cells that also secrete various cytokines and growth factors to support repair of damaged tissues. In this study, we examined the role of oxi...

    Authors: Mariko Moriyama, Hiroyuki Moriyama, Ayaka Ueda, Yusuke Nishibata, Hanayuki Okura, Akihiro Ichinose, Akifumi Matsuyama and Takao Hayakawa

    Citation: BMC Cell Biology 2012 13:21

    Content type: Research article

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  32. HS-1-associated protein X-1 (Hax-1), is a multifunctional protein that has sequence homology to Bcl-2 family members. HAX-1 knockout animals reveal that it plays an essential protective role in the central nervou...

    Authors: Bin Li, Qingsong Hu, Ranjie Xu, Haigang Ren, Erkang Fei, Dong Chen and Guanghui Wang

    Citation: BMC Cell Biology 2012 13:20

    Content type: Research article

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  33. MeCP2 (CpG-binding protein 2) is a nuclear multifunctional protein involved in several cellular processes, like large-scale chromatin reorganization and architecture, and transcriptional regulation. In recent ...

    Authors: Federica Babbio, Ilaria Castiglioni, Chiara Cassina, Marzia Bruna Gariboldi, Christian Pistore, Elena Magnani, Gianfranco Badaracco, Elena Monti and Ian Marc Bonapace

    Citation: BMC Cell Biology 2012 13:19

    Content type: Research article

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  34. The tumor microenvironment contains a vast array of pro- and anti-inflammatory cytokines that alter myelopoiesis and lead to the maturation of immunosuppressive cells known as myeloid-derived suppressor cells ...

    Authors: Ines Hammami, Jingkui Chen, Frederic Murschel, Vincenzo Bronte, Gregory De Crescenzo and Mario Jolicoeur

    Citation: BMC Cell Biology 2012 13:18

    Content type: Research article

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  35. Current methods of isolation of muscle satellite cells from different animal species are highly variable making inter-species comparisons problematic. This variation mainly stems from the use of different prot...

    Authors: Belinda Baquero-Perez, Suresh V Kuchipudi, Rahul K Nelli and Kin-Chow Chang

    Citation: BMC Cell Biology 2012 13:16

    Content type: Methodology article

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  36. Proteins functioning in the same biological pathway tend to be transcriptionally co-regulated or form protein-protein interactions (PPI). Multiple spatially and temporally regulated events are coordinated duri...

    Authors: Aaron R Tipton, Kexi Wang, Peter Oladimeji, Shermeen Sufi, Zhidong Gu and Song-Tao Liu

    Citation: BMC Cell Biology 2012 13:15

    Content type: Research article

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  37. Yeast has numerous mechanisms to survive stress. Deletion of myosin type II (myo1Δ) in Saccharomyces cerevisiae results in a cell that has defective cytokinesis. To survive this genetically induced stress, this b...

    Authors: Glorivee Pagán-Mercado, Ednalise Santiago-Cartagena, Pearl Akamine and José R Rodríguez-Medina

    Citation: BMC Cell Biology 2012 13:13

    Content type: Research article

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  38. The behaviour of tumour cells depends on factors such as genetics and the tumour microenvironment. The latter plays a crucial role in normal mammary gland development and also in breast cancer initiation and p...

    Authors: Vanisri Raviraj, Sandra Fok, Jifei Zhao, Hsin-Ya Chien, J Guy Lyons, Erik W Thompson and Lilian Soon

    Citation: BMC Cell Biology 2012 13:12

    Content type: Research article

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  39. Aurora kinases (Aurora-A, B and C) belong to a family of conserved serine/threonine kinases which are key regulators of cell cycle progression. Aurora-A and Aurora-B are expressed in somatic cells and involved...

    Authors: Jabbar Khan, Sanaullah Khan, Sobia Attaullah, Ijaz Ali and Shahid Niaz Khan

    Citation: BMC Cell Biology 2012 13:8

    Content type: Research article

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    The Erratum to this article has been published in BMC Cell Biology 2012 13:17

  40. Interferon-α (IFN-α) exerts an anti-tumor effect at least through induction of apoptosis in a variety of types including B lymphoma cells. We recently found that IFN-α induced a sustained activation of c-Jun NH2-...

    Authors: Noriko Yanase, Miho Hayashida, Yuki Kanetaka-Naka, Akinori Hoshika and Junichiro Mizuguchi

    Citation: BMC Cell Biology 2012 13:7

    Content type: Research article

    Published on:

2018 Journal Metrics

  • Citation Impact

    3.485 - 2-year Impact Factor
    3.227 - 5-year Impact Factor
    0.857 - Source Normalized Impact per Paper (SNIP)
    1.403 - SCImago Journal Rank (SJR)

    Usage 
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