Sahlender DA, Roberts RC, Arden SD, Spudich G, Taylor MJ, Luzio JP, Kendrick-Jones J, Buss F: Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis. Cell Biol. 2005, 169: 285-295. 10.1083/jcb.200501162.
Article
CAS
Google Scholar
Anborgh PH, Godin C, Pampillo M, Dhami GK, Dale LB, Cregan SP, Truant R, Ferguson SS: Inhibition of metabotropic glutamate receptor signaling by the huntingtin-binding protein optineurin. J Biol Chem. 2005, 280: 34840-34848. 10.1074/jbc.M504508200.
Article
CAS
PubMed
Google Scholar
Zhu G, Wu CJ, Zhao Y, Ashwell JD: Optineurin negatively regulates TNFα-induced NF-κB activation by competing with NEMO for ubiquitinated RIP. Curr Biol. 2007, 17: 1438-1443. 10.1016/j.cub.2007.07.041.
Article
CAS
PubMed
Google Scholar
Sudhakar C, Nagabhushana A, Jain N, Swarup G: NF-κB Mediates Tumor Necrosis Factor α-Induced Expression of Optineurin, a Negative Regulator of NF-κB. PLoS ONE. 2009, 4: e5114-10.1371/journal.pone.0005114.
Article
PubMed Central
PubMed
Google Scholar
Park BC, Tibudan M, Samaraweera M, Shen X, Yue BY: Interaction between two glaucoma genes, optineurin and myocilin. Genes Cells. 2007, 12: 969-979. 10.1111/j.1365-2443.2007.01102.x.
Article
CAS
PubMed
Google Scholar
Weisschuh N, Alavi MV, Bonin M, Wissinger B: Identification of genes that are linked with optineurin expression using a combined RNAi--microarray approach. Exp Eye Res. 2007, 85: 450-461. 10.1016/j.exer.2007.06.012.
Article
CAS
PubMed
Google Scholar
Rezaie T, Sarfarazi M: Molecular cloning, genomic structure, and protein characterization of mouse optineurin. Genomics. 2005, 85: 131-138. 10.1016/j.ygeno.2004.10.011.
Article
CAS
PubMed
Google Scholar
Rezaie T, Waitzman DM, Seeman JL, Kaufman PL, Sarfarazi M: Molecular cloning and expression profiling of optineurin in the Rhesus monkey. Invest Ophthalmol Vis Sci. 2005, 46: 2404-2410. 10.1167/iovs.04-1243.
Article
PubMed
Google Scholar
De Marco N, Buon M, Troise F, Diez-Roux G: Optineurin increases cell survival and translocates to the nucleus in a RAB8 dependent manner upon an apoptotic stimulus. J Biol Chem. 2006, 281: 16147-16156. 10.1074/jbc.M601467200.
Article
CAS
PubMed
Google Scholar
Kroeber M, Ohlmann A, Russell P, Tamm ER: Transgenic studies on the role of optineurin in the mouse eye. Exp Eye Res. 2006, 2: 1075-1085. 10.1016/j.exer.2005.11.004.
Article
Google Scholar
Rezaie T, Child A, Hitchings R, Brice G, Miller L, Coca-Prados M, Heon E, Krupin T, Ritch R, Kreutzer D, Crick RP, Sarfarazi M: Adult-onset primary open-angle glaucoma caused by mutations in optineurin. Science. 2002, 295: 1077-1079. 10.1126/science.1066901.
Article
CAS
PubMed
Google Scholar
Schwamborn K, Weil R, Courtois G, Whiteside ST, Israel A: Phorbol esters and cytokines regulate the expression of the NEMO-related protein, a molecule involved in a NF-kappa B-independent pathway. J Biol Chem. 2000, 275: 22780-22789. 10.1074/jbc.M001500200.
Article
CAS
PubMed
Google Scholar
Au JS, Puri C, Ihrke G, Kendrick-Jones J, Buss F: Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cells. J Cell Biol. 2007, 177: 103-114. 10.1083/jcb.200608126.
Article
PubMed Central
CAS
PubMed
Google Scholar
del Toro D, Alberch J, Lazaro-Dieguez F, Martin-Ibanez R, Xifro X, Egea G, Canals JM: Mutant Huntingtin impairs post-Golgi trafficking to lysosomes by delocalizing optineurin/Rab8 complex from the Golgi apparatus. Mol Biol Cell. 2009, 20: 1478-1492. 10.1091/mbc.E08-07-0726.
Article
PubMed Central
CAS
PubMed
Google Scholar
Park BC, Shen X, Samaraweera M, Yue BY: Studies of optineurin, a glaucoma gene: Golgi fragmentation and cell death from overexpression of wild-type and mutant optineurin in two ocular cell types. Am J Pathol. 2006, 169: 1976-1989. 10.2353/ajpath.2006.060400.
Article
PubMed Central
CAS
PubMed
Google Scholar
Hattula K, Peränen J: FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis. Curr Biol. 2000, 10: 1603-1606. 10.1016/S0960-9822(00)00864-2.
Article
CAS
PubMed
Google Scholar
Zerial M, McBride H: Rab proteins as membrane organizers. Nat Rev Mol Cell Biol. 2001, 2: 107-117. 10.1038/35052055.
Article
CAS
PubMed
Google Scholar
Pfeffer SR: Rab GTPases: specifying and deciphering organelle identity and function. Trends Cell Biol. 2001, 11: 487-491. 10.1016/S0962-8924(01)02147-X.
Article
CAS
PubMed
Google Scholar
Huber LA, de Hoop MJ, Dupree P, Zerial M, Simons K, Dotti C: Protein transport to the dendritic plasma membrane of cultured neurons is regulated by rab8p. J Cell Biol. 1993, 123: 47-55. 10.1083/jcb.123.1.47.
Article
CAS
PubMed
Google Scholar
Ang AL, Fölsch H, Koivisto UM, Pypaert M, Mellman I: The Rab8 GTPase selectively regulates AP-1B-dependent basolateral transport in polarized Madin-Darby canine kidney cells. J Cell Biol. 2003, 163: 339-350. 10.1083/jcb.200307046.
Article
PubMed Central
CAS
PubMed
Google Scholar
Hattula K, Furuhjelm J, Tikkanen J, Tanhuanpää K, Laakkonen P, Peränen J: Characterization of the Rab8-specific membrane traffic route linked to protrusion formation. J Cell Sci. 2006, 119: 4866-4877. 10.1242/jcs.03275.
Article
CAS
PubMed
Google Scholar
Huber LA, Pimplikar S, Parton RG, Virta H, Zerial M, Simons K: Rab8, a small GTPase involved in vesicular traffic between the TGN and the basolateral plasma membrane. Cell Biol. 1993, 123: 35-45. 10.1083/jcb.123.1.35.
Article
CAS
Google Scholar
Ang AL, Taguchi T, Francis S, Fölsch H, Murrells LJ, Pypaert M, Warren G, Mellman I: Recycling endosomes can serve as intermediates during transport from the Golgi to the plasma membrane of MDCK cells. J Cell Biol. 2004, 16: 731-743.
Google Scholar
Henry L, Sheff DR: Rab8 regulates basolateral secretory, but not recycling, traffic at the recycling endosome. Mol Biol Cell. 2008, 19: 2059-2068. 10.1091/mbc.E07-09-0902.
Article
PubMed Central
CAS
PubMed
Google Scholar
DiFiglia M, Sapp E, Chase K, Schwarz C, Meloni A, Young C, Martin E, Vonsattel JP, Carraway R, Reeves SA, Boyce FM, Aronin N: Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons. Neuron. 1995, 14: 1075-1081. 10.1016/0896-6273(95)90346-1.
Article
CAS
PubMed
Google Scholar
Hoffner G, Kahlem P, Djian P: Perinuclear localization of huntingtin as a consequence of its binding to microtubules through an interaction with beta-tubulin: relevance to Huntington's disease. J Cell Sci. 2002, 115: 941-958.
CAS
PubMed
Google Scholar
Maxfield FR, McGraw TE: Endocytic Recycling. Nat Rev Mol Cell Biol. 2004, 5: 121-132. 10.1038/nrm1315.
Article
CAS
PubMed
Google Scholar
Hopkins CR: Intracellular routing of transferrin and transferrin receptors in epidermoid carcinoma A431 cells. Cell. 1983, 35: 321-330. 10.1016/0092-8674(83)90235-0.
Article
CAS
PubMed
Google Scholar
Hopkins CR, Trowbridge IS: Internalization and processing of transferrin and the transferrin receptor in human carcinoma A431 cells. J Cell Biol. 1983, 97: 508-521. 10.1083/jcb.97.2.508.
Article
CAS
PubMed
Google Scholar
Yamashiro D, Tycko B, Fluss S, Maxfield FR: Segregation of transferrin to a mildly acidic (pH 6.5) para-Golgi compartment in the recycling pathway. Cell. 1984, 37: 789-800. 10.1016/0092-8674(84)90414-8.
Article
CAS
PubMed
Google Scholar
Ullrich O, Reinsch S, Urbé S, Zerial M, Parton RG: Rab11 regulates recycling through the pericentriolar recycling endosome. J Cell Biol. 1996, 135: 913-924. 10.1083/jcb.135.4.913.
Article
CAS
PubMed
Google Scholar
Chen W, Feng Y, Chen D, Wandinger-Ness A: Rab11 is required for trans-golgi network-to-plasma membrane transport and a preferential target for GDP dissociation inhibitor. Mol Biol Cell. 1998, 9: 3241-3257.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ren M, Xu G, Zeng J, De Lemos-Chiarandini C, Adesnik M, Sabatini DD: Hydrolysis of GTP on rab11 is required for the direct delivery of transferrin from the pericentriolar recycling compartment to the cell surface but not from sorting endosomes. Proc Natl Acad Sci USA. 1998, 95: 6187-6192. 10.1073/pnas.95.11.6187.
Article
PubMed Central
CAS
PubMed
Google Scholar
Mellman I: Endocytosis and molecular sorting. Annu Rev Cell Dev Biol. 1996, 12: 575-625. 10.1146/annurev.cellbio.12.1.575.
Article
CAS
PubMed
Google Scholar
Quigley HA: Neuronal death in glaucoma. Prog Retin Eye Res. 1999, 18: 39-57. 10.1016/S1350-9462(98)00014-7.
Article
CAS
PubMed
Google Scholar
Chalasani ML, Radha V, Gupta V, Agarwal N, Balasubramanian D, Swarup G: A glaucoma-associated mutant of optineurin selectively induces death of retinal ganglion cells which is inhibited by antioxidants. Invest Ophthalmol Vis Sci. 2007, 48: 1607-1614. 10.1167/iovs.06-0834.
Article
PubMed
Google Scholar
Sheff DR, Daro EA, Hull M, Mellman I: The receptor recycling pathway contains two distinct populations of early endosomes with different sorting functions. J Cell Biol. 1999, 145: 123-139. 10.1083/jcb.145.1.123.
Article
PubMed Central
CAS
PubMed
Google Scholar
Aung T, Rezaie T, Okada K, Viswanathan AC, Child AH, Brice G, Bhattacharya SS, Lehmann OJ, Sarfarazi M, Hitchings RA: Clinical features and course of patients with glaucoma with the E50K mutation in the optineurin gene. Invest Ophthalmol Vis Sci. 2005, 46: 2816-2822. 10.1167/iovs.04-1133.
Article
PubMed
Google Scholar
Hicke L, Dunn R: Regulation of membrane transport by ubiquitin and ubiquitin-binding proteins. Annu Rev Cell Dev Biol. 2003, 19: 141-172. 10.1146/annurev.cellbio.19.110701.154617.
Article
CAS
PubMed
Google Scholar
Mukhopadhyay D, Riezman H: Proteasome-independent functions of ubiquitin in endocytosis and signaling. Science. 2007, 315: 201-205. 10.1126/science.1127085.
Article
CAS
PubMed
Google Scholar
Raiborg C, Bache KG, Gillooly DJ, Madshus IH, Stang E, Stenmark H: Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes. Nat Cell Biol. 2002, 4: 394-398. 10.1038/ncb791.
Article
CAS
PubMed
Google Scholar
Journo C, Filipe J, About F, Chevalier SA, Afonso PV, Brady JN, Flynn D, Tangy F, Israël A, Vidalain PO, Mahieux R, Weil R: NRP/Optineurin Cooperates with TAX1BP1 to potentiate the activation of NF-kappaB by human T-lymphotropic virus type 1 tax protein. PLoS Pathog. 2009, 5: e1000521-10.1371/journal.ppat.1000521.
Article
PubMed Central
PubMed
Google Scholar
Morton S, Hesson L, Peggie M, Cohen P: Enhanced binding of TBK1 by an optineurin mutant that causes a familial form of primary open angle glaucoma. FEBS Lett. 2008, 582: 997-1002. 10.1016/j.febslet.2008.02.047.
Article
CAS
PubMed
Google Scholar
Gould GW, Lippincott-Schwartz J: New roles for endosomes: from vesicular carriers to multi-purpose platforms. Nat Rev Mol Cell Biol. 2009, 10: 287-292. 10.1038/nrm2652.
Article
PubMed Central
CAS
PubMed
Google Scholar
Sadowski L, Pilecka I, Miaczynska M: Signaling from endosomes: location makes a difference. Exp Cell Res. 2009, 315: 1601-1609. 10.1016/j.yexcr.2008.09.021.
Article
CAS
PubMed
Google Scholar
Vrabec JP, Levin LA: The neurobiology of cell death in glaucoma. Eye. 2007, 21: S11-14. 10.1038/sj.eye.6702880.
Article
CAS
PubMed
Google Scholar
Pease ME, McKinnon SJ, Quigley HA, Kerrigan-Baumrind LA, Zack DJ: Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma. Invest Ophthalmol Vis Sci. 2000, 41: 764-774.
CAS
PubMed
Google Scholar
Quigley HA, McKinnon SJ, Zack DJ, Pease ME, Kerrigan-Baumrind LA, Kerrigan DF, Mitchell RS: : Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats. Invest Ophthalmol Vis Sci. 2000, 41: 3460-3466.
CAS
PubMed
Google Scholar
Krishnamoorthy RR, Agarwal P, Prasanna G, Vopat K, Lambert W, Sheedlo HJ, Pang IH, Shade D, Wordinger RJ, Yorio T, Clark AF, Agarwal N: Characterization of a transformed rat retinal ganglion cell line. Mol Brain Res. 2001, 86: 1-12. 10.1016/S0169-328X(00)00224-2.
Article
CAS
PubMed
Google Scholar
Van Bergen NJ, Wood JP, Chidlow G, Trounce IA, Casson RJ, Ju WK, Weinreb RN, Crowston J: Re-characterisation of the RGC-5 retinal ganglion cell line. Invest Ophthalmol Vis Sci. 2009, 50: 4267-4272. 10.1167/iovs.09-3484.
Article
PubMed
Google Scholar
Gupta V, Swarup G: Evidence for a role of transmembrane protein p25 in localization of protein tyrosine phosphatase TC48 to the ER. J Cell Sci. 2007, 119: 1703-1714. 10.1242/jcs.02885.
Article
Google Scholar
He TC, Zhou S, da Costa LT, Yu J, Kinzler KW, Vogelstein B: A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci USA. 1998, 95: 2509-2514. 10.1073/pnas.95.5.2509.
Article
PubMed Central
CAS
PubMed
Google Scholar
Jain N, Sudhakar Ch, Swarup G: Tumor necrosis factor-alpha-induced caspase-1 gene expression. Role of p73. FEBS J. 2007, 274: 4396-4407. 10.1111/j.1742-4658.2007.05969.x.
Article
CAS
PubMed
Google Scholar
Jain N, Gupta S, Sudhakar Ch, Radha V, Swarup G: Role of p73 in regulating human caspase-1 gene transcription induced by interferon-γ and cisplatin. J Biol Chem. 2005, 280: 36664-36673. 10.1074/jbc.M413261200.
Article
CAS
PubMed
Google Scholar
Paliwal P, Radha V, Swarup G: Regulation of p73 by Hck through kinase-dependent and independent mechanisms. BMC Mol Biol. 2007, 8: 45-10.1186/1471-2199-8-45.
Article
PubMed Central
PubMed
Google Scholar
Gauthier LR, Charrin BC, Borrell-Pagès M, Dompierre JP, Rangone H, Cordelières FP, De Mey J, MacDonald ME, Lessmann V, Humbert S, Saudou F: Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell. 2004, 118: 127-138. 10.1016/j.cell.2004.06.018.
Article
CAS
PubMed
Google Scholar
Shivakrupa R, Radha V, Sudhakar Ch, Swarup G: Physical and functional interaction between Hck tyrosine kinase and guanine nucleotide exchange factor C3G results in apoptosis, which is independent of C3G catalytic domain. J Biol Chem. 2003, 278: 52188-52194. 10.1074/jbc.M310656200.
Article
CAS
PubMed
Google Scholar