Edited by Juan C Sáez.
Volume 17 Supplement 1
Proceedings of the International Gap Junction Conference 2015
Research
Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. Articles have undergone the journal's standard peer review process for supplements. The Supplement Editor declares that they have no competing interests.
Valparaiso, Chile28 March - 2 April 2015
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Citation: BMC Cell Biology 2016 17(Suppl 1):18
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Molecular mechanisms regulating formation, trafficking and processing of annular gap junctions
Internalization of gap junction plaques results in the formation of annular gap junction vesicles. The factors that regulate the coordinated internalization of the gap junction plaques to form annular gap junc...
Citation: BMC Cell Biology 2016 17(Suppl 1):S22 -
Role of connexins and pannexins during ontogeny, regeneration, and pathologies of bone
Electron micrographs revealed the presence of gap junctions in osteoblastic cells over 40 years ago. These intercellular channels formed from connexins are present in bone forming osteoblasts, bone resorbing o...
Citation: BMC Cell Biology 2016 17(Suppl 1):S19 -
Connexins and pannexins in neuronal development and adult neurogenesis
Connexins and pannexins share very similar structures and functions; they also exhibit overlapping expression in many stages of neuronal development. Here, we review evidence implicating connexin- and pannexin...
Citation: BMC Cell Biology 2016 17(Suppl 1):S10 -
Activity-dependent plasticity of electrical synapses: increasing evidence for its presence and functional roles in the mammalian brain
Gap junctions mediate electrical synaptic transmission between neurons. While the actions of neurotransmitter modulators on the conductance of gap junctions have been extensively documented, increasing evidenc...
Citation: BMC Cell Biology 2016 17(Suppl 1):14 -
Characteristics and plasticity of electrical synaptic transmission
Electrical synapses are an omnipresent feature of nervous systems, from the simple nerve nets of cnidarians to complex brains of mammals. Formed by gap junction channels between neurons, electrical synapses al...
Citation: BMC Cell Biology 2016 17(Suppl 1):13 -
Connexinopathies: a structural and functional glimpse
Mutations in human connexin (Cx) genes have been related to diseases, which we termed connexinopathies. Such hereditary disorders include nonsyndromic or syndromic deafness (Cx26, Cx30), Charcot Marie Tooth di...
Citation: BMC Cell Biology 2016 17(Suppl 1):S17 -
Connexins: substrates and regulators of autophagy
Connexins mediate intercellular communication by assembling into hexameric channel complexes that act as hemichannels and gap junction channels. Most connexins are characterized by a very rapid turn-over in a ...
Citation: BMC Cell Biology 2016 17(Suppl 1):S20 -
Connexin and pannexin channels in cancer
Communication among cells via direct cell-cell contact by connexin gap junctions, or between cell and extracellular environment via pannexin channels or connexin hemichannels, is a key factor in cell function ...
Citation: BMC Cell Biology 2016 17(Suppl 1):S12 -
Expression and function of pannexins in the inner ear and hearing
Pannexin (Panx) is a gene family encoding gap junction proteins in vertebrates. So far, three isoforms (Panx1, 2 and 3) have been identified. All of three Panx isoforms express in the cochlea with distinct exp...
Citation: BMC Cell Biology 2016 17(Suppl 1):16 -
The absence of dysferlin induces the expression of functional connexin-based hemichannels in human myotubes
Mutations in the gene encoding for dysferlin cause recessive autosomal muscular dystrophies called dysferlinopathies. These mutations induce several alterations in skeletal muscles, including, inflammation, in...
Citation: BMC Cell Biology 2016 17(Suppl 1):15 -
Regulation of gap junction channels and hemichannels by phosphorylation and redox changes: a revision
Post-translational modifications of connexins play an important role in the regulation of gap junction and hemichannel permeability. The prerequisite for the formation of functional gap junction channels is th...
Citation: BMC Cell Biology 2016 17(Suppl 1):11
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Journal Impact Factor: 2.4
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Source Normalized Impact per Paper (SNIP): 0.684
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